Primary Tumor Resection and Survival in Patients with Stage IV Gastric Cancer
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Korean Gastric Cancer Assoc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: The aim of this study was to determine whether surgical resection of the primary tumor contributes to survival in patients with metastatic gastric cancer. Materials and Methods: A total of 288 patients with metastatic gastric cancer from the Akdeniz University, Antalya Training and Research Hospital, and the Meram University of Konya database were retrospectively analyzed. The effect of primary tumor resection on survival of patients with metastatic gastric cancer was investigated using the log-rank test. Kaplan-Meier survival estimates were calculated. Multivariate analysis was performed using Cox proportional hazards regression modeling. Results: The median overall survival was 12.0 months (95% confidence intewrval [CI], 10.4 similar to 13.6 months) and 7.8 months (95% CI, 5.5 similar to 10.0 months) for patients with and without primary tumor resection, respectively (P<0.001). The median progression-free survival was 8.3 months (95% CI, 7.1 similar to 9.5 months) and 6.2 months (95% CI, 5.8 similar to 6.7 months) for patients with and without primary tumor resection, respectively (P=0.002). Conclusions: Non-curative gastrectomy in patients with metastatic gastric cancer might increase their survival rate regardless of the occurrence of life-threatening tumor-related complications.
Açıklama
Anahtar Kelimeler
Stomach Neoplasms, Surgery, Mortality
Kaynak
Journal Of Gastric Cancer
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
16
Sayı
2
