Serum ischemia-modified albumin level and its association with cardiovascular risk factors in obese children and adolescents

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dc.contributor.authorBaysal, Tamer
dc.contributor.authorAlp, Hayrullah
dc.contributor.authorKoc, Nesibe
dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorKaraarslan, Sevim
dc.date.accessioned2024-02-23T14:29:49Z
dc.date.available2024-02-23T14:29:49Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractBackground: Serum ischemia modified albumin (IMA) levels have been previously studied and found to correlate with some anthropometric and laboratory measurements in adult obesity. IMA had not been studied in obese children and adolescents. Objective: The aim of the study is to analyze serum IMA levels and to evaluate their correlation with cardiovascular risk factors in obese children and adolescents with and without metabolic syndrome (MS). Subjects and methods: Sixty-one obese children/adolescents and 33 healthy children were included in the study. The obese group was divided into four subgroups, including MS (n=25), non-MS (n=36), liver steatosis (n=19) and non-liver steatosis (n=42) groups. Blood was collected to analyze biochemical parameters and IMA. Epicardial adipose tissue thickness was measured with echocardiography, and liver steotosis was determined with ultrasonography for each subject. Results: Body mass index (BMI), waist circumferences (WC), left ventricular mass (LVM) and epicardial adipose tissue (EAT) thickness were significantly higher in obese subjects. Serum IMA levels were significantly higher in the metabolic syndrome (MS) and hepatosteotosis groups. Additionally, LVM and EAT thickness were found to be correlated with serum IMA levels in these groups. Conclusions: Our study suggests that serum IMA levels may be used to predict cardiovascular risk in obese children with MS and hepatosteotosis. This may be related to the duration of obesity in childhood ending in adulthood.en_US
dc.identifier.doi10.1515/jpem-2012-0191
dc.identifier.endpage944en_US
dc.identifier.issn0334-018X
dc.identifier.issue9.Ekien_US
dc.identifier.pmid23426823en_US
dc.identifier.scopus2-s2.0-84867770400en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage935en_US
dc.identifier.urihttps://doi.org/10.1515/jpem-2012-0191
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14867
dc.identifier.volume25en_US
dc.identifier.wosWOS:000309757300019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal Of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiovascular Risken_US
dc.subjectChildren And Adolescentsen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectHepatosteotosisen_US
dc.subjectIschemia Modified Albuminen_US
dc.subjectMetabolic Syndromeen_US
dc.titleSerum ischemia-modified albumin level and its association with cardiovascular risk factors in obese children and adolescentsen_US
dc.typeArticleen_US

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