Familial Mediterranean fever: Health-related quality of life and associated variables in a national cohort

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dc.contributor.authorBodur, Hatice
dc.contributor.authorYurdakul, Fatma Gul
dc.contributor.authorDuruoz, Mehmet Tuncay
dc.contributor.authorCay, Hasan Fatih
dc.contributor.authorUcar, Ulku
dc.contributor.authorKeskin, Yasar
dc.contributor.authorSargin, Betul
dc.date.accessioned2024-02-23T14:40:48Z
dc.date.available2024-02-23T14:40:48Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjectives: This study aims to evaluate the effectivity of Familial Mediterranean Fever Quality of Life (FMF-QoL) Scale for the measurement of QoL in patients with FMF and to perform correlations between related clinical variables in Turkish patients. Patients and methods: This multicenter prospective study performed between December 2017 and November 2018 included 974 FMF patients (334 males, 640 females; median age: 35; range, 26 to 45 years). Sociodemographic characteristics and clinical features were recorded. All participants were asked to complete the FMF-QoL Scale, Short Form-36 (SF-36), Hospital Anxiety and Depression Scale (HADS), Health Assessment Questionnaire (HAQ), and Functional Assessment of Chronic Illness Therapy (FACIT) Scale. Results: The median FMF-QoL Scale score was 26. Higher FMF-QoL Scale scores were shown to be related to female sex, illiteracy or primary education, monthly low-income (US$<300), smoking, late-onset FMF (>20 years), a higher number of attacks per month (>1/month), and severe disease. FMF-QoL Scale scores were correlated negatively with subscales of SF-36, and positively with HADS-anxiety and HADS-depression scores, HAQ and FACIT. Conclusion: Female sex, smoking, lower educational status, more severe disease, fatigue, and functional impairment were associated with poor QoL. FMF-QoL Scale was noted as a valid and simple patient-reported outcome instrument and correlated with the SF-36 scale.en_US
dc.identifier.doi10.46497/ArchRheumatol.2021.8215
dc.identifier.endpage166en_US
dc.identifier.issn2148-5046
dc.identifier.issn1309-0283
dc.identifier.issue2en_US
dc.identifier.pmid34527919en_US
dc.identifier.scopus2-s2.0-85107826111en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage159en_US
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2021.8215
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16591
dc.identifier.volume36en_US
dc.identifier.wosWOS:000657513700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoinflammatory Diseasesen_US
dc.subjectDepressionen_US
dc.subjectFatigueen_US
dc.subjectHereditaryen_US
dc.subjectLife Qualityen_US
dc.titleFamilial Mediterranean fever: Health-related quality of life and associated variables in a national cohorten_US
dc.typeArticleen_US

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