Tag SNP selection using clonal selection and majority voting algorithms

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dc.contributor.authorIlhan, Ilhan
dc.contributor.authorTezel, Gulay
dc.date.accessioned2024-02-23T14:29:43Z
dc.date.available2024-02-23T14:29:43Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractResearchers should select a suitable subgroup that includes all SNPs and represents the rest of the SNPs with little error for very large-scale association studies. The SNPs included in the subgroup are tag SNPs or haplotype tag SNPs (htSNPs). When selecting the tag SNPs, it is critical to accurately predict and identify the smallest number of tag SNPs with minimum error. This study used the Clonal Selection Algorithm (CLONALG) to decide on the tag SNPs to be included in the subgroup. In addition, the study proposed a new method called CSMV, which used the Majority Voting (MV) method to predict the rest of the SNPs. This method was compared with the BPSO method and the CLONTagger with parameter optimisation method using datasets of different sizes. According to the experimental results of the study, the CSMV method could determine the tag SNPs with significantly higher accuracy than the other two methods.en_US
dc.description.sponsorshipNecmettin Erbakan University Scientific Research Projects Coordinatorship, Konya, Turkeyen_US
dc.description.sponsorshipThis study is supported by Necmettin Erbakan University Scientific Research Projects Coordinatorship, Konya, Turkey. The authors would like to thank the editors and anonymous reviewers of this manuscript for their very helpful suggestions.en_US
dc.identifier.doi10.1504/IJDMB.2016.10003176
dc.identifier.endpage311en_US
dc.identifier.issn1748-5673
dc.identifier.issn1748-5681
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage290en_US
dc.identifier.urihttps://doi.org/10.1504/IJDMB.2016.10003176
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14834
dc.identifier.volume16en_US
dc.identifier.wosWOS:000397990200002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherInderscience Enterprises Ltden_US
dc.relation.ispartofInternational Journal Of Data Mining And Bioinformaticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbcen_US
dc.subjectArtificial Bee Colony Algorithmen_US
dc.subjectClonalgen_US
dc.subjectClonal Selection Algorithmen_US
dc.subjectMajority Votingen_US
dc.subjectSvmen_US
dc.subjectSupport Vector Machineen_US
dc.subjectTag Snpsen_US
dc.titleTag SNP selection using clonal selection and majority voting algorithmsen_US
dc.typeArticleen_US

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