First Evaluation of P Dispersion and Tp-e Parameters in Electrocardiograms of Children with Diabetic Ketoacidosis

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dc.contributor.authorEgil, Oguz
dc.contributor.authorSap, Fatih
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorOflaz, Mehmet Burhan
dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorBaysal, Tamer
dc.date.accessioned2024-02-23T14:38:10Z
dc.date.available2024-02-23T14:38:10Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractObjective: Diabetic ketoacidosis (DKA) is an important complication of type 1 diabetes mellitus. We aimed to evaluate the effect of metabolic disorders of DKA on electrocardiography (ECG) parameters in children. Methods: This study was performed between December 2018 and March 2020 and included 39 children with DKA and 40 healthy children. Three ECGs (one before and two after treatment) were obtained from the patient group. P-wave dispersion (Pd), QT dispersion (QTd), QTc dispersion (QTcd), Tp-e intervals, and the ratios of Tp-e/QT and Tp-e/QTc were measured electrocardiographically. ECG parameters from children with DKA and healthy controls were compared statistically. Results: The mean age of the patient group was 10.50 +/- 4.12 years. There was no significant difference in terms of age, gender, weight, height and body mass index between patients and controls. In the patient group, a statistically significant increase was found in Pd, QTd and QTcd in the initial ECG compared to the second and third ECGs. Also, when the first and third ECGs were compared, a significant increase in Tp-e and Tp-e/QT was evident in the first ECG. There was a significant difference in the values of Pd, QTd, QTcd, Tp-e and Tp-e/QT in the first ECGs, obtained before DKA treatment, and those values obtained from the control group. Conclusion: This is the first article evaluating Pd and Tp-e parameters in children with DKA. Cardiac arrhythmia risk markers were increased in children with DKA compared to controls. Therefore, clinicians should be aware of the possibility of developing new arrhythmias during DKA treatment.en_US
dc.description.sponsorshipNecmettin Erbakan University's Scientific Research Project Coordinator [181518017]en_US
dc.description.sponsorshipThis study was funded by Necmettin Erbakan University's Scientific Research Project Coordinator (decision no. 181518017, dated 05.10.2018) , which allowed supply of electrocardiography device and its equipments.en_US
dc.identifier.doi10.4274/jcrpe.galenos.2021.2021.0165
dc.identifier.endpage45en_US
dc.identifier.issn1308-5727
dc.identifier.issn1308-5735
dc.identifier.issue1en_US
dc.identifier.pmid34538047en_US
dc.identifier.scopus2-s2.0-85125682597en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage37en_US
dc.identifier.urihttps://doi.org/10.4274/jcrpe.galenos.2021.2021.0165
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16398
dc.identifier.volume14en_US
dc.identifier.wosWOS:000778594700005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of Clinical Research In Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiac Arrhythmiaen_US
dc.subjectChildrenen_US
dc.subjectDiabetic Ketoacidosisen_US
dc.subjectElectrocardiographyen_US
dc.titleFirst Evaluation of P Dispersion and Tp-e Parameters in Electrocardiograms of Children with Diabetic Ketoacidosisen_US
dc.typeArticleen_US

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