Management of Patent Ductus Arteriosus in Preterm Patients Who Were Given Surfactant

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dc.contributor.authorYilmaz, Fatma Hilal
dc.contributor.authorEmiroglu, Nuriye
dc.contributor.authorOflaz, Mehmet Burhan
dc.contributor.authorGultekin, Nazli Dilay
dc.contributor.authorYucel, Mehmet
dc.contributor.authorKececi, Ramazan
dc.contributor.authorAltunhan, Huseyin
dc.date.accessioned2024-02-23T14:38:25Z
dc.date.available2024-02-23T14:38:25Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractAim: Respiratory distress syndrome (RDS) and perinatal asphyxia are known to be risk factors in hemodynamically significant Patent Ductus Arteriosus (hsPDA). In this study, we aimed to reveal scientific data in respiratory distressed preterm infants in the light of the current literature and to discuss the management of PDA in babies born at 33d weeks of gestation and up to 33d weeks which we have treated and followed in our unit. Materials and Methods: The medical records of premature infants treated at Necmettin Erbakan University Neonatal Intensive Care Unit (NICU) between January 2016 and January 2019 were retrospectively evaluated. Results: Between January 2016 and January 2019, 476 patients born prior to 33d gestational weeks were admitted to our unit.. PDA was detected in 149 of these patients because of RDS due to the surfactants. In 112 (75.1%) of these patients, the PDA closed spontaneously within the first week of life. Thirty-seven (24.8%) patients developed hs-PDA. The incidence of premature retinopathy (ROP), bronchopulmonary dysplasia (BPD), and late neonatal sepsis morbidity was significantly elevated during the hospitalization (p=0.05, p=0.01, p=0.06). Invasive mechanical ventilation, non-invasive mechanical ventilation, and free oxygen requirement times were found to be longer (p= 0.0001, p= 0.004, p= 0.014). Complete enteral nutrition and discharge times were longer in the treated group (p= 0.03, p= 0.002). We identified the presence of Small for Gestational Age (SGA) (r = 0.30 p = 0.04) and low birth weight (r = 0.99 p = 0.02) in logistic regression analysis of the factors affecting the PDA as meaningful results. Discussion: The presence of hs-PDA in infants with RDS is directly proportional to the birth week and weight, the presence of SGA reduces the frequency of hs-PDAs, the presence of hs-PDA is associated with ROP, BPD, and late sepsis. The presence of hs-PDA has been found to be correlated with prolonged respiratory support and delayed discharge.en_US
dc.identifier.doi10.4328/ACAM.20044
dc.identifier.endpage215en_US
dc.identifier.issn2667-663X
dc.identifier.issue3en_US
dc.identifier.startpage211en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20044
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16524
dc.identifier.volume11en_US
dc.identifier.wosWOS:000572683400012en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPretermen_US
dc.subjectPatent Ductus Arteriosusen_US
dc.subjectRespiratory Distress Syndromeen_US
dc.subjectSurfactanten_US
dc.titleManagement of Patent Ductus Arteriosus in Preterm Patients Who Were Given Surfactanten_US
dc.typeArticleen_US

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