Evaluation of Changes in The Hematological Parameters, Lipid Profile and Depressive Symptoms Before and After Smoking Cessation Treatment

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dc.contributor.authorDagistan, Fatma
dc.contributor.authorKutlu, Ruhusen
dc.date.accessioned2024-02-23T14:34:27Z
dc.date.available2024-02-23T14:34:27Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractIntroduction: Tobacco dependence is a cluster of behavioural, cognitive, and physiological phenomena. We aimed to investigate the changes in the hematological parameters, lipid profile and depressive symptoms before and after smoking cessation. Methods: In this intervention study, 150 casesadmitted to the d in is to quit smoking and stopped smoking for at least three months were investigated. All participants have received motivational interview and appropriate medical treatment (varenicline, bupropion, nicotine replacement therapy). We designed the study to evaluate the effects of cigarette smoking on some biochemical markers and depressive symptoms. Results: Motivational interviews were conducted on all participants, and 68,7% (n = 103) were treated with varenicline, 19,3% (n=29) with bupropion and 12% (n=18) with nicotine replacement therapy (NRT). There was a statistically significant relationship between the treatment method and the smoking cessation duration (p=0.002). Cessation period was longer in the group using varenicline. After quitting smoking, the Beck Depression Scores (BDS) decreased significantly (p<0.001). In cases with smoking duration between 3-6 months, the levels of carbon monoxide (CO) (p<0.001), white blood count (WBC) (p<0.001), hematocrit (p=0.003), hemoglobin (Hb) (p=0.002) and mean corpuscular volume (MCV) (p<0.001) decreased significantly. Conclusions: In our study, positive changes were observed in hematologic, biochemical parameters and depressive symptoms after quitting smoking. So, it is important that the society should be informed about the dangers of smoking. In particular, primary health care physicians should ask each patient whether they smoke or not, and encourage to quit smoking.en_US
dc.identifier.doi10.30621/jbachs.2019.723
dc.identifier.endpage176en_US
dc.identifier.issn2458-8938
dc.identifier.issn2564-7288
dc.identifier.issue3en_US
dc.identifier.startpage170en_US
dc.identifier.urihttps://doi.org/10.30621/jbachs.2019.723
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15622
dc.identifier.volume3en_US
dc.identifier.wosWOS:000488481200010en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAves Press Ltden_US
dc.relation.ispartofJournal Of Basic And Clinical Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmoking Cessationen_US
dc.subjectHematological Parametersen_US
dc.subjectLipid Profileen_US
dc.subjectDepressionen_US
dc.titleEvaluation of Changes in The Hematological Parameters, Lipid Profile and Depressive Symptoms Before and After Smoking Cessation Treatmenten_US
dc.typeArticleen_US

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