The effect of chronotypes on follow-up outcomes of patients with substance use disorder

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dc.contributor.authorCiner, Ozlem Akcay
dc.contributor.authorCilli, Ali Savas
dc.contributor.authorYazici, Ahmet Bulent
dc.contributor.authorBakay, Hasan
dc.contributor.authorGica, Sakir
dc.date.accessioned2024-02-23T14:00:12Z
dc.date.available2024-02-23T14:00:12Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractSubstance use disorder (SUD) can have circadian characteristics and individuals with evening chronotype are more prone to addiction. In this study, the effect of chronotypes on the treatment outcomes of SUD was investigated. The study included 66 patients who were diagnosed with SUD according to DSM-5. Two clinical interviews were conducted at 6-month intervals, and remission/relapse status was evaluated at the second interview. The Structured Clinical Interview Form for DSM-IV Axis I Disorders (SCID-I), Addiction Profile Index Practitioner Form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Pittsburg Sleep Quality Index and Morningness-Eveningness Questionnaire (MEQ) were applied to the patients. MEQ scores of relapsed patients were found to be different in terms of eveningness than those in remission (45.62 +/- 8.70 versus 49.75 +/- 7.60, p = 0.045). As the craving and addiction profile index total scores (addiction severity) increased, eveningness chronotype scores also increased (r = - 0.387 and r = - 0.286, respectively). The mean scores of craving and BDI were higher in relapsed patients compared to those in remission (p = 0.003 and p = 0.015, respectively). Our results suggest that patients with SUD had a lower morningness chronotype than the general population; additionally, more relapsed patients had an eveningness chronotype. Thus, chronotypes may play a role in the onset, prevention, and treatment outcome of SUD.en_US
dc.identifier.doi10.1007/s41105-023-00496-8
dc.identifier.issn1446-9235
dc.identifier.issn1479-8425
dc.identifier.scopus2-s2.0-85175246748en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1007/s41105-023-00496-8
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11503
dc.identifier.wosWOS:001099564100002en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Japan Kken_US
dc.relation.ispartofSleep And Biological Rhythmsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronobiologyen_US
dc.subjectChronotypeen_US
dc.subjectRelapseen_US
dc.subjectRemissionen_US
dc.subjectSubstance Use Disorderen_US
dc.titleThe effect of chronotypes on follow-up outcomes of patients with substance use disorderen_US
dc.typeArticleen_US

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