The Value of Neutrophil:Lymphocyte Ratio and Platelet:Lymphocyte Ratio in Predicting Clinical Severity in Children with Carbon Monoxide Poisoning

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dc.contributor.authorBagci, Zafer
dc.contributor.authorArslan, Abdullah
dc.contributor.authorArslan, Derya
dc.date.accessioned2024-02-23T13:59:49Z
dc.date.available2024-02-23T13:59:49Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective To compare the values of neutrophil:lymphocyte ratio (NLR), platelet:lymphocyte ratio (PLR), and mean platelet volume (MPV) with carboxyhemoglobin (COHb) and lactate levels in children with acute CO intoxication. Methods In this retrospective study, the patients were divided into two groups: mild-to-moderate carbon monoxide poisoning (COP) (COHb 10%-20%) and severe COP (COHb > 20%) according to the COHb levels in the application. All patients were compared in terms of NLR, PLR, and MPV parameters according to the severity of poisoning and the high lactate levels (>= 2.2 mmol/L). Results A total of 261 children with COP were included in the study. The number of patients with mild-to-moderate COP was 183 (70.1%), and the number of patients with severe COP was 78 (29.9%). NLR [2.57 (3.27), 1.65 (1.93), (p = 0.001)] and PLR [123.0 (88.24), 92.8 (54.1), (p = 0.001)] values of mild-to-moderate COP were statistically significantly lower than the severe COP group. In the group with high lactate level, PLR values were significantly lower [120.1 (71.9), 100.2 (85.4), (p = 0.017)]. NLR and PLR values were found to be predictive of severe COP. Conclusion NLR and PLR can be used for detection of clinical severity in patients with COP. PLR can be used in conjunction with lactate levels to detect tissue-level exposure in patients with COP.en_US
dc.identifier.doi10.1007/s12098-021-03704-w
dc.identifier.endpage1126en_US
dc.identifier.issn0019-5456
dc.identifier.issn0973-7693
dc.identifier.issue11en_US
dc.identifier.pmid33725287en_US
dc.identifier.scopus2-s2.0-85102532966en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1121en_US
dc.identifier.urihttps://doi.org/10.1007/s12098-021-03704-w
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11336
dc.identifier.volume88en_US
dc.identifier.wosWOS:000629490600001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofIndian Journal Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarbon Monoxide Poisoningen_US
dc.subjectNeutrophilen_US
dc.subjectLymphocyte Ratioen_US
dc.subjectPlateleten_US
dc.subjectLymphocyte Ratioen_US
dc.subjectLactateen_US
dc.titleThe Value of Neutrophil:Lymphocyte Ratio and Platelet:Lymphocyte Ratio in Predicting Clinical Severity in Children with Carbon Monoxide Poisoningen_US
dc.typeArticleen_US

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