Procalcitonin Level at 24 Hours of Age May be Predictive for Transient Tachypnea of the Newborn

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dc.contributor.authorTarakci, Nuriye
dc.contributor.authorAltunhan, Huseyin
dc.contributor.authorSari, Eyup
dc.contributor.authorUyar, Mehmet
dc.date.accessioned2024-02-23T14:16:59Z
dc.date.available2024-02-23T14:16:59Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjective It is an important problem to differentiate transient tachypnea of the newborn (TTN) from bacterial pneumonia or other conditions in patients admitted to Neonatal Intensive Care Unit. The aimof this study was to evaluate the predictive value of procalcitonin (PCT) for TTN. Methods A total of 52 infants were contained in the study. The patients were divided into three groups. Group 1 consisted of patients with pronounced grunting at more than 2 hours postnatal age (n = 16). Group 2 consisted of patients whose grunt was reduced or gone at 2 hours postnatal age but in whom tachypnea persisted until 24 hours postnatal age (n = 18). Group 3 consisted of patients with minimal or no respiratory distress at 24 hours postnatal age (n = 18). In all groups, PCT concentrations were determined at birth and 24 hours postnatal age. Results PCT concentrations at birth were significantly higher in Group 1 than other groups, but there was no difference between Groups 2 and 3. PCT concentrations at 24 hours postnatal age were significantly higher in Groups 1 and 2 than Group 3. No difference was found between Group 1 and Group 2 at 24 hours postnatal age. All PCT concentrations in Group 3 were significantly lower than other groups. PCT thresholds for the diagnosis of TTN were 0.44 ng/mL at birth (sensitivity 58%, specificity 50%) and 5.11 ng/mL at 24 hours postnatal age (sensitivity 79.4%, specificity 89.1%). Conclusion Serial PCT measurements at birth and postnatal 24 hours may be helpful in differentiating between pneumonia and TTN. Further researches are needed to confirm this initial study.en_US
dc.identifier.doi10.1055/s-0040-1718432
dc.identifier.endpage311en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85094912252en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage307en_US
dc.identifier.urihttps://doi.org/10.1055/s-0040-1718432
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12870
dc.identifier.volume15en_US
dc.identifier.wosWOS:000579423100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal Of Pediatric Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProcalcitoninen_US
dc.subjectTransient Tachypnea Of The Newbornen_US
dc.subjectNeonatal Sepsisen_US
dc.titleProcalcitonin Level at 24 Hours of Age May be Predictive for Transient Tachypnea of the Newbornen_US
dc.typeArticleen_US

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