Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy (3D-CRT) and Intensity Modulated Radiotherapy Techniques (IMRT) with Radiotherapy Dose Simulations For Left-Sided Mastectomy Patients

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dc.contributor.authorAras, Serhat
dc.contributor.authorIkizceli, Turkan
dc.contributor.authorAktan, Meryem
dc.date.accessioned2024-02-23T14:41:04Z
dc.date.available2024-02-23T14:41:04Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractObjective: To compare 3-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT) techniques on the target tissue and critical organ doses in terms of dosimetry, during treatment planning of patient's post-mastectomy radiotherapy (PMRT) to the left chest wall. Materials and Methods: Twenty breast cancer patients with left-sided post-mastectomy have selected for PMRT both 3D-CRT and IMRT techniques. Dosimetric calculation of dose simulation in Eclipse treatment planning system have been performed. Organs at risk with the maximum dose, minimum dose, mean. dose, D95, conformity and homogeneity indexes and total monitor unit for the Planning Target Volume were compared in terms of the critical organ doses. Results: There was no significant difference between the two treatment planning techniques in terms of maximum, minimum, mean dose and heterogeneity index (p>0.05). At low doses, the dose received at the heart was significantly lower with the 3D-CRT technique, but there was no significant difference between the two techniques at the maximum and average doses in the high dose regions. Conclusion: For PMRT to the left chest wall, IMRT significantly improves the conformity of plan and reduce the high-dose volumes of ipsilateral lung and heart compared to 3D-CRT, but 3D-CRT is superior in terms of low-dose volume.en_US
dc.identifier.doi10.5152/ejbh.2019.4619
dc.identifier.endpage89en_US
dc.identifier.issn2587-0831
dc.identifier.issue2en_US
dc.identifier.pmid31001609en_US
dc.identifier.scopus2-s2.0-85086900017en_US
dc.identifier.startpage85en_US
dc.identifier.urihttps://doi.org/10.5152/ejbh.2019.4619
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16693
dc.identifier.volume15en_US
dc.identifier.wosWOS:000463466900003en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofEuropean Journal Of Breast Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLeft-Sided Mastectomyen_US
dc.subjectThree-Dimensional Conformal Radiotherapyen_US
dc.subjectIntensity-Modulated Radiotherapyen_US
dc.subjectDose Simulationen_US
dc.subjectDosimetryen_US
dc.titleDosimetric Comparison of Three-Dimensional Conformal Radiotherapy (3D-CRT) and Intensity Modulated Radiotherapy Techniques (IMRT) with Radiotherapy Dose Simulations For Left-Sided Mastectomy Patientsen_US
dc.typeArticleen_US

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