The prognostic significance of the 18F-fluorodeoxyglucose positron emission tomography/computed tomography in early-stage nonsmall cell lung cancer

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dc.contributor.authorGeredeli, Caglayan
dc.contributor.authorArtac, Mehmet
dc.contributor.authorKocak, Ismail
dc.contributor.authorKoral, Lokman
dc.contributor.authorSakin, Abdullah
dc.contributor.authorAltinok, Tamer
dc.contributor.authorKaya, Bugra
dc.date.accessioned2024-02-23T14:37:53Z
dc.date.available2024-02-23T14:37:53Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractContext: The prognostic criteria for early-stage nonsmall cell lung cancer (NSCLC) wait to be explored. Aim: In this study, our aim was to evaluate the prognostic significance of the positron emission tomography/computed tomography (PET/CT) maximum standardized uptake value (SUVmax) value of the primary tumor in patients with a diagnosis of early-stage NSCLC who received surgical treatment. Settings and Design: This was a multicenter retrospective design. Materials and Methods: Patients who had been diagnosed with early-stage NSCLC and who underwent surgery for the condition were included in this study. The preoperative fluorodeoxyglucose (18F-FDG) PET/CT results of the patients were retrospectively accessed from their medical files. The disease-free survival (DFS) rates of patients who had SUVmax values above and below the determined cutoff value were compared. Statistical Analysis Used: SPSS version 22 and Kaplan-Meier method were used for statistical analysis. Results: A total of 92 patients were included in the study. The median age of the patients was 60 years (range: 36-79). The determined cutoff SUVmax value of the primary tumor was 13.6. A comparison of the DFS rates of the patients with an SUVmax value above and below 13.6 revealed a significant difference in patients with Stage I (22.9 months vs. 50.3 months; P = 0.02) and Stage II (28 months vs. 40.4 months; P = 0.04), Stage I + II (43.5 months vs. 26.1 months; P = 0,02), and Stage IIIA (14.7 months vs. 13.6 months; P = 0.92) NSCLC. Conclusions: We found that in early-stage NSCLC patients, the SUVmax value of the primary mass in 18F FDG PET/CT was a prognostic indicator for the DFS rates.en_US
dc.description.sponsorshipSelcuk University Research Support System, Konya, Turkeyen_US
dc.description.sponsorshipThis study was funded by Selcuk University Research Support System, Konya, Turkey.en_US
dc.identifier.doi10.4103/jcrt.JCRT_911_17
dc.identifier.endpage821en_US
dc.identifier.issn0973-1482
dc.identifier.issn1998-4138
dc.identifier.issue4en_US
dc.identifier.pmid32930124en_US
dc.identifier.scopus2-s2.0-85091051417en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage816en_US
dc.identifier.urihttps://doi.org/10.4103/jcrt.JCRT_911_17
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16259
dc.identifier.volume16en_US
dc.identifier.wosWOS:000585412200019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofJournal Of Cancer Research And Therapeuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject18f-Fluorodeoxyglucose Positron Emission Tomographyen_US
dc.subjectComputed Tomographyen_US
dc.subjectEarly-Stage Nonsmall Cell Lung Canceren_US
dc.subjectMaximum Standardized Uptake Valueen_US
dc.titleThe prognostic significance of the 18F-fluorodeoxyglucose positron emission tomography/computed tomography in early-stage nonsmall cell lung canceren_US
dc.typeArticleen_US

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