The effect of low dose ionizing radiation exposure on dynamic thiol-disulfide homeostasis and ischemia modified albumin levels: an observational study

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dc.contributor.authorArican, Sule
dc.contributor.authorDertli, Ramazan
dc.contributor.authorBaktik, Suleyman
dc.contributor.authorHacibeyoglu, Gulcin
dc.contributor.authorErol, Atilla
dc.contributor.authorUlukaya, Sinan Oguzhan
dc.contributor.authorGoger, Esra
dc.date.accessioned2024-02-23T14:02:20Z
dc.date.available2024-02-23T14:02:20Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractBackground: The primary objective of this study was to investigate the effect of low dose ionizing radiation exposure on thiol/disulfide homeostasis and ischemia modified albumin levels. The secondary objective is to compare thiol/disulfide homeostasis and ischemia modified albumin levels among the personnel exposed to low dose ionizing radiation in anesthesia application areas, in and out of the Operation room. Methods: The study included a total of 90 volunteers aged between 18 and 65 years old, with 45 personnel working in a setting with potential for radiation exposure (Exposed Group) and 45 personnel in a setting without radiation exposure (Control Group). Their native thiol, total thiol, disulphide, albumine and IMA levels were measured. Exposed group included personnel who were exposed to radiation outside the operating room - Operation room (-) Group and inside the Operating room - Operation room (+) Group. Results: Albumin, native and total thiol levels were significantly lower in the participants exposed to radiation in the anesthesia application area, no statistically significant difference was found in terms of disulfide and ischemia modified albumin levels. In the Operation room (-) group exposed to radiation, native thiol and total thiol values were significantly lower compared to the Operation room (+) groups. Conclusion: Awareness of being in danger of oxidative stress should be established in personnel exposed to radiation in the anesthesia application area following low dose ionizing radiation exposure, and the necessary measures should be taken. (C) 2020 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda.en_US
dc.identifier.doi10.1016/j.bjan.2020.02.009
dc.identifier.endpage239en_US
dc.identifier.issn0034-7094
dc.identifier.issn1806-907X
dc.identifier.issue3en_US
dc.identifier.pmid32482354en_US
dc.identifier.scopus2-s2.0-85085648837en_US
dc.identifier.startpage233en_US
dc.identifier.urihttps://doi.org/10.1016/j.bjan.2020.02.009
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11654
dc.identifier.volume70en_US
dc.identifier.wosWOS:000560503300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isopoen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofRevista Brasileira De Anestesiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAneghesiaen_US
dc.subjectIschemia Modified Albuminen_US
dc.subjectRadiationen_US
dc.subjectThiolen_US
dc.titleThe effect of low dose ionizing radiation exposure on dynamic thiol-disulfide homeostasis and ischemia modified albumin levels: an observational studyen_US
dc.typeArticleen_US

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