Effects of atrial electromechanical delay and ventriculoatrial conduction over the atrial functions in patients with frequent extrasystole and preserved ejection fraction

dc.contributor.authorGurbuz, Ahmet Seyfeddin
dc.contributor.authorOzturk, Semi
dc.contributor.authorKilicgedik, Alev
dc.contributor.authorAkgun, Taylan
dc.contributor.authorKalkan, Mehmet Emin
dc.contributor.authorDemir, Serdar
dc.contributor.authorEfe, Suleyman Cagan
dc.date.accessioned2024-02-23T14:24:33Z
dc.date.available2024-02-23T14:24:33Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractBackground The deterioration of left atrial and ventricular functions was demonstrated in patients with frequent ventricular extrasystole (fVES). The exact pathophysiology of left atrial dysfunction in patients with fVES is unclear. Retrograde ventriculoatrial conduction (VAC) often accompanies fVES, which may contribute to atrial dysfunction. We investigated whether atrial electromechanical delay and VAC are related to these atrial functions in patients with frequent right ventricular outflow tract (RVOT) VES and preserved ejection fraction (pEF). Methods This study included 21 patients with pEF (eight males, 48 +/- 11 years), who had experienced more than 10 000 RVOT-VES during 24-h Holter monitoring and had undergone electrophysiological study/ablation. The study also included 20 healthy age- and sex-matched control subjects. Transthoracic echocardiography was performed on all of the subjects. Atrial conduction time was obtained by using tissue Doppler imaging. Strain analysis was performed with two-dimensional speckle tracking echocardiography. Results The peak atrial longitudinal strain was significantly impaired in patients with fVES (P = 0.01). In addition, although the interatrial and left atrial conduction delay times were significantly different between each group (P < 0.001, P < 0.001), the right atrial conduction delay times were similar. When patients with fVES were divided into groups depending on the existence of retrograde VAC, atrial deformation parameters and conduction delay time did not significantly differ between either group. Conclusion Frequent RVOT-VES causes left atrial dysfunction. This information is obtained through strain analyses and recordings of left atrial conduction times in patients with pEF. Regardless, retrograde VAC is not related to atrial dysfunction.en_US
dc.identifier.doi10.1111/pace.13606
dc.identifier.endpage326en_US
dc.identifier.issn0147-8389
dc.identifier.issn1540-8159
dc.identifier.issue3en_US
dc.identifier.pmid30653680en_US
dc.identifier.scopus2-s2.0-85061038208en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage321en_US
dc.identifier.urihttps://doi.org/10.1111/pace.13606
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14006
dc.identifier.volume42en_US
dc.identifier.wosWOS:000460951100006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPace-Pacing And Clinical Electrophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtrial Conduction Timeen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectElectrophysiological Studyen_US
dc.subjectLeft Atrial Deformationen_US
dc.subjectSpeckle-Tracking Strain Imagingen_US
dc.subjectVentricular Extrasystoleen_US
dc.subjectVentriculoatrial Conductionen_US
dc.titleEffects of atrial electromechanical delay and ventriculoatrial conduction over the atrial functions in patients with frequent extrasystole and preserved ejection fractionen_US
dc.typeArticleen_US

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