Retinal Nerve Fiber Layer Thickness in Children With ADHD

dc.contributor.authorHerguner, Arzu
dc.contributor.authorAlpfidan, Ismail
dc.contributor.authorYar, Ahmet
dc.contributor.authorErdogan, Erkan
dc.contributor.authorMetin, Ozge
dc.contributor.authorSakarya, Yasar
dc.contributor.authorHerguner, Sabri
dc.date.accessioned2024-02-23T14:27:04Z
dc.date.available2024-02-23T14:27:04Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractObjectives: The current study aims to compare retinal nerve fiber layer (RNFL) thickness, macular thickness, and macular volume between children with ADHD and a control group. Method: The study group included children with ADHD and the control group consisted of age- and gender-matched participants without any psychiatric disorder. In all participants, RNFL thickness, macular thickness, and macular volume were measured by using spectral domain-optical coherence tomography (SD-OCT). ADHD symptom severity was evaluated by using parent-report measures, including Conners' Parent Rating Scale-Revised: Short Form (CPRS-R: S) and the Strengths and Difficulties Questionnaire: Parent Form (SDQ: P). Results: We compared 90 eyes of 45 children with ADHD and 90 eyes of 45 controls. ADHD group had significantly lower RNFL thickness only in nasal quadrant than the controls. The remaining RNFL quadrants, macular thickness, and volume were not significantly different between groups. There was a reverse correlation between RNFL thickness and ADHD symptom severity. Conclusion: This is the first study examining the RNFL thickness in ADHD. Our findings showed that nasal RNFL thickness was lower, indicating reduced unmyelinated axons in the retina of children with ADHD. The results of this study support the evidence that ADHD involves a lag in cortical maturation and this is measurable in the retina.en_US
dc.identifier.doi10.1177/1087054716664412
dc.identifier.endpage626en_US
dc.identifier.issn1087-0547
dc.identifier.issn1557-1246
dc.identifier.issue7en_US
dc.identifier.pmid27535944en_US
dc.identifier.scopus2-s2.0-85045510409en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage619en_US
dc.identifier.urihttps://doi.org/10.1177/1087054716664412
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14440
dc.identifier.volume22en_US
dc.identifier.wosWOS:000430086700002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal Of Attention Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdhden_US
dc.subjectChildrenen_US
dc.subjectMacular Thicknessen_US
dc.subjectOptical Coherence Tomographyen_US
dc.subjectRetinal Nerve Fiber Layer Thicknessen_US
dc.titleRetinal Nerve Fiber Layer Thickness in Children With ADHDen_US
dc.typeArticleen_US

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