Ethyl Alcohol Versus Botulinum Toxin A: A Comparative Study of the Visual and Histopathological Outcomes in the Rabbit Anterior Auricular Muscle Model

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dc.contributor.authorInce, Bilsev
dc.contributor.authorUyanik, Orkun
dc.contributor.authorOltulu, Pembe
dc.contributor.authorIsmayilzade, Majid
dc.contributor.authorDadaci, Mehmet
dc.contributor.authorSavaci, Nedim
dc.date.accessioned2024-02-23T14:21:09Z
dc.date.available2024-02-23T14:21:09Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractBACKGROUND Botulinum toxin has long been known for its paralytic effects at the neuromuscular junction. Although it has been widely used for vascular and nervous tissues, there has been no study of the aesthetic effects of the application of ethanol to muscle tissues to date. OBJECTIVE The authors aimed to demonstrate the effects of the application of ethanol to muscle tissues after an intramuscular injection and to compare the effects of botulinum toxin A (BTA) and ethanol. METHODS AND MATERIALS: A total of 28 rabbits were divided into 4 groups (n = 7 each). Botulinum toxin A (5 units) and different concentrations of ethanol (5 cc) were injected into the left and right anterior auricular muscles of all rabbits, respectively. Ear ptosis was assessed, and histopathological examination was performed after all rabbits were euthanized in the eighth week. RESULTS Muscle function was affected earlier in ethanol-treated ears than in botulinum-treated ears; however, the ptotic effect lasted for a significantly shorter duration in ethanol-injected ears than in BTA-applied ears. CONCLUSION Ethanol can block muscle function reversibly and can serve as an alternative to BTA, particularly when rapid results are desirable.en_US
dc.identifier.doi10.1097/DSS.0000000000002600
dc.identifier.endpage1666en_US
dc.identifier.issn1076-0512
dc.identifier.issn1524-4725
dc.identifier.issue12en_US
dc.identifier.pmid32852430en_US
dc.identifier.scopus2-s2.0-85097003455en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1661en_US
dc.identifier.urihttps://doi.org/10.1097/DSS.0000000000002600
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13451
dc.identifier.volume46en_US
dc.identifier.wosWOS:000619177600041en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofDermatologic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleEthyl Alcohol Versus Botulinum Toxin A: A Comparative Study of the Visual and Histopathological Outcomes in the Rabbit Anterior Auricular Muscle Modelen_US
dc.typeArticleen_US

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