Treatment of Isolated Cataplexy With Low-dose Aripiprazole in an Adolescent Patient

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dc.contributor.authorUzun, Necati
dc.contributor.authorAkinci, Mehmet Akif
dc.date.accessioned2024-02-23T14:23:34Z
dc.date.available2024-02-23T14:23:34Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractBackground Cataplexy is a clinical entity that is characterized by transient muscle tone loss that mostly occurring as a part of narcolepsy. On the other hand, isolated cataplexy (IC) (hereditary cataplexy) is defined as loss of muscle tone that is not accompanied by narcolepsy. Emotional reactions may trigger IC episodes. Additionally, human leukocyte antigen (HLA) DQB1 alleles were shown to be related to IC. Various antidepressants are useful in the treatment of IC; however, there is limited knowledge on the use of antipsychotics in the treatment of IC. Case Report A 16-year-old adolescent girl was consulted child and adolescent psychiatry outpatient clinic with complaint of sudden episodes of loss of muscle tone. Her HLA typing showed HLA DQB1*03 haplotype. She was diagnosed with IC and was prescribed aripiprazole 2.5 mg/d and her IC symptoms disappeared and never recurred over 6 months of follow-up. Conclusions In this case report, we present an adolescent girl with IC that is successfully treated with aripiprazole, an antipsychotic. This case report suggests that aripiprazole may be safely used in some adolescents who diagnosed with IC.en_US
dc.identifier.doi10.1097/WNF.0000000000000398
dc.identifier.endpage126en_US
dc.identifier.issn0362-5664
dc.identifier.issn1537-162X
dc.identifier.issue4en_US
dc.identifier.pmid32590615en_US
dc.identifier.scopus2-s2.0-85088485165en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage125en_US
dc.identifier.urihttps://doi.org/10.1097/WNF.0000000000000398
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13608
dc.identifier.volume43en_US
dc.identifier.wosWOS:000556608600009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofClinical Neuropharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIsolated Cataplexyen_US
dc.subjectNarcolepsyen_US
dc.subjectAripiprazoleen_US
dc.subjectAdolescenten_US
dc.titleTreatment of Isolated Cataplexy With Low-dose Aripiprazole in an Adolescent Patienten_US
dc.typeReview Articleen_US

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