Cancer among syrian refugees living in Konya Province, Turkey

dc.contributor.authorKutluk, Tezer
dc.contributor.authorKoc, Mehmet
dc.contributor.authorOner, Irem
dc.contributor.authorBabalioglu, Ibrahim
dc.contributor.authorKirazli, Meral
dc.contributor.authorAydin, Sinem
dc.contributor.authorAhmed, Fahad
dc.date.accessioned2024-02-23T14:31:09Z
dc.date.available2024-02-23T14:31:09Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground With more than 3.6 million Syrian refugees Turkey hosts the world's largest number of Syrians. Considering the morbidity, mortality, and healthcare spending, cancer is one of the leading health and economic burden for patients and healthcare systems. However, very limited information available in the scientific literature to understand the burden and characteristics of cancer in countries hosting Syrian refugees. The aim of the present study is to evaluate the demographic and clinical characteristics, treatment outcome of Syrian cancer patients living in Konya, Turkey. Methods We retrospectively reviewed medical records of Syrian cancer patients at three major institutions from 2005 to 2020. The information regarding demographic and clinical characteristics of patients were identified. The number of days between the first symptom and diagnosis was considered as the diagnostic interval. Patients who failed to attend clinics within four weeks of appointment were assumed abandoned treatment. Survival curves were estimated using the Kaplan-Meier method. Results We identified 230 adult and 38 children refugee diagnosed with cancer during the study period. With regards to adult patients, there were 114 (49.6%) male and 116 (50.4%) female. The median age at diagnosis was 52.4, 47.3 years for male, female respectively. The five most common cancer by site among all were; breast (24.8%), colorectal (10.9%), lung (7.4%), central nervous system (CNS) (7.0%), and stomach (5.2%). 93 (40.4%) had metastatic disease at diagnosis. The overall survival probability was 37.5% at five years for the adult population. Data were extracted for 20 boys and 18 girls with childhood cancer. Their median age at diagnosis was 5.8 and 6.0 years respectively. The three most common childhood cancer were; leukemias (21.1%), lymphomas (21.1%), and CNS (13.2%). Excluding leukemia, 13 (43.3%) of childhood cancer cases had the advanced disease at diagnosis. Three year survival probality was 69.5%. The median diagnostic interval for adult and childhood cancer was 96.5 (IQR = 53-165) and 23 (IQR = 13.5-59) days respectively. Twenty-one adults and four children had treatment abandonment. Conclusion This study contributes to understanding the burden of cancer among Syrian refugees living in Konya, growing health issue for refugees. Larger and prospective studies will help to measure the real burden and compare the difference in cancer risk factors, care, and outcomes among the refugee and host populations.en_US
dc.description.sponsorshipUK Research and Innovation GCRF Research for Health in Conflict ( R4HC-MENA); National Institute of Health Research Project [131207]; [ES/P010962/1]en_US
dc.description.sponsorshipThis study was funded through the UK Research and Innovation GCRF Research for Health in Conflict (R4HC-MENA); developing capability, partnerships and research in the Middle and Near East (MENA). Grant number ES/P010962/1. RS is funded by National Institute of Health Research Project No131207. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en_US
dc.identifier.doi10.1186/s13031-022-00434-4
dc.identifier.issn1752-1505
dc.identifier.issue1en_US
dc.identifier.pmid35101060en_US
dc.identifier.scopus2-s2.0-85123995666en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s13031-022-00434-4
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15050
dc.identifier.volume16en_US
dc.identifier.wosWOS:000748909200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofConflict And Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCanceren_US
dc.subjectSyrian Refugeesen_US
dc.titleCancer among syrian refugees living in Konya Province, Turkeyen_US
dc.typeArticleen_US

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