Delta variant effect on the clinical course of adolescent COVID-19 patients

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dc.contributor.authorCaglar, Hanife Tugce
dc.contributor.authorPekcan, Sevgi
dc.contributor.authorYilmaz, Asli Imran
dc.contributor.authorUnal, Gokcen
dc.contributor.authorAkcan, Ozge Metin
dc.contributor.authorUnsacar, Mahmut Z.
dc.contributor.authorOzdemir, Mehmet
dc.date.accessioned2024-02-23T13:03:31Z
dc.date.available2024-02-23T13:03:31Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractObjective The clinical course of new COVID-19 variants in adolescents is still unknown. The aim of this study is to evaluate the clinical characteristics of COVID-19 in adolescents and compare the differences between the original version and the delta variant. Materials and Methods The medical records of patients aged 10-18 years treated for COVID-19 between April 1, 2020 and March 31, 2022 were retrospectively reviewed. Patients were divided into four groups (asymptomatic, mild, moderate, and severe) for COVID-19 severity and into two groups according to the diagnosis date (first-second year). The primary endpoint of the study was hospital admission. Results The mean age of patients was 171.81 +/- 29.5 months, and most of them were males (n: 435, 53.3%). While the patient number was 296 (43.52%) in the first year of pandemic, it raised to 520 (54.11%) in the second year (p < 0.01). The severity of COVID-19 was mild in 667 (81.7%) patients. In the comparison of patients according to the diagnosis date (first-second years); the parameters of anosmia, ageusia, weakness, muscle pain, vomiting, hospital admission, and length of stay in hospital were statistically different (p < 0.05). In the comparison of hospitalized patients between years, the necessity of oxygen support (p < 0.001), endotracheal intubation rates (p < 0.05), length of stay in the hospital (p < 0.001), and the severity of COVID-19 (p < 0.05) was significantly higher in the second year. Conclusion The clinical course for adolescents diagnosed with COVID-19 has linearly changed with the delta variant. Our results confirmed that the delta variant is more transmissible, requires more oxygen support, increases endotracheal intubation, and prolongs the length of stay in the hospital.en_US
dc.identifier.doi10.1002/ppul.26166
dc.identifier.endpage121en_US
dc.identifier.issn8755-6863
dc.identifier.issn1099-0496
dc.identifier.issue1en_US
dc.identifier.pmid36177518en_US
dc.identifier.scopus2-s2.0-85139430907en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage115en_US
dc.identifier.urihttps://doi.org/10.1002/ppul.26166
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10653
dc.identifier.volume58en_US
dc.identifier.wosWOS:000864189300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatric Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdolescenten_US
dc.subjectCovid-19en_US
dc.subjectDelta Varianten_US
dc.titleDelta variant effect on the clinical course of adolescent COVID-19 patientsen_US
dc.typeArticleen_US

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