The Relationship of Epicardial Adipose Tissue and Cardiovascular Disease in Chronic Kidney Disease and Hemodialysis Patients

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dc.contributor.authorTurkmen, Kultigin
dc.contributor.authorOzer, Hakan
dc.contributor.authorKusztal, Mariusz
dc.date.accessioned2024-02-23T14:35:10Z
dc.date.available2024-02-23T14:35:10Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractCardiovascular diseases remain the most common cause of morbidity and mortality in chronic kidney disease patients undergoing hemodialysis. Epicardial adipose tissue (EAT), visceral fat depot of the heart, was found to be associated with coronary artery disease in cardiac and non-cardiac patients. Additionally, EAT has been proposed as a novel cardiovascular risk in the general population and in end-stage renal disease patients. It has also been shown that EAT, more than other subcutaneous adipose tissue deposits, acts as a highly active organ producing several bioactive adipokines, and proinflammatory and proatherogenic cytokines. Therefore, increased visceral adiposity is associated with proinflammatory activity, impaired insulin sensitivity, increased risk of atherosclerosis, and high morbidity and mortality in hemodialysis patients. In the present review, we aimed to demonstrate the role of EAT in the pathophysiological mechanisms of increased cardiovascular morbidity and mortality in hemodialysis patients.en_US
dc.identifier.doi10.3390/jcm11051308
dc.identifier.issn2077-0383
dc.identifier.issue5en_US
dc.identifier.pmid35268399en_US
dc.identifier.scopus2-s2.0-85125186974en_US
dc.identifier.urihttps://doi.org/10.3390/jcm11051308
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15913
dc.identifier.volume11en_US
dc.identifier.wosWOS:000768916000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofJournal Of Clinical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectCardiovascular Morbidity And Mortalityen_US
dc.subjectHemodialysisen_US
dc.titleThe Relationship of Epicardial Adipose Tissue and Cardiovascular Disease in Chronic Kidney Disease and Hemodialysis Patientsen_US
dc.typeArticleen_US

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