P-wave parameters and cardiac repolarization indices: Does menopausal status matter?

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dc.contributor.authorDogan, Umuttan
dc.contributor.authorDogan, Nasuh Utku
dc.contributor.authorBasarir, Ahmet Ozgur
dc.contributor.authorYildirim, Serkan
dc.contributor.authorCelik, Cetin
dc.contributor.authorIncesu, Feyzanur
dc.contributor.authorOzdemir, Kurtulus
dc.date.accessioned2024-02-23T14:12:51Z
dc.date.available2024-02-23T14:12:51Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractBackground and purpose: Data regarding electrocardiographic characteristics of postmenopausal women are lacking. In this prospective, cross-sectional study, electrocardiographic P-wave parameters and cardiac repolarization indices of age-matched pre- and postmenopausal healthy women were compared. We hypothesized that menopausal status would have a significant effect on cardiac electrical activity and hence electrocardiography (ECG) recordings. Materials and methods: Twelve-lead ECG recordings were obtained from 125 consecutively recruited postmenopausal healthy women aged between 44 and 54 years. The control group consisted of 125 age-matched premenopausal women. P-wave parameters and cardiac repolarization indices were measured and compared with respect to menopausal status. Results: Demographic features of premenopausal and postmenopausal women were comparable. There were no significant differences between two groups regarding mean values of heart rate, maximum and minimum P-wave duration, P-wave dispersion, maximum and minimum QT interval, and QT dispersion. Mean values of QT interval obtained from lead V5 were also similar. Corrected values which were calculated according to Bazett and Fridericia formulas also did not differ between the groups. Mean values of Tpeak to Tend (TpTe) (p < 0.001) and corrected TpTe (p = 0.001) intervals obtained from lead V5 were significantly shorter in postmenopausal women when compared to those without menopause. Conclusion: Tpeak to Tend interval decreased significantly while QT intervals and P-wave parameters did not change in postmenopausal women when compared to premenopausal women. Association of these findings with changes in levels of sex steroids and their prognostic implications need to be elucidated with further studies. (C) 2012 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jjcc.2012.04.001
dc.identifier.endpage337en_US
dc.identifier.issn0914-5087
dc.identifier.issue3.Nisen_US
dc.identifier.pmid22658698en_US
dc.identifier.scopus2-s2.0-84866553085en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage333en_US
dc.identifier.urihttps://doi.org/10.1016/j.jjcc.2012.04.001
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12213
dc.identifier.volume60en_US
dc.identifier.wosWOS:000310107500030en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofJournal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMenopauseen_US
dc.subjectElectrocardiographyen_US
dc.subjectP-Wave Dispersionen_US
dc.subjectCardiac Repolarization Indicesen_US
dc.subjectTpeak To Tend Intervalen_US
dc.titleP-wave parameters and cardiac repolarization indices: Does menopausal status matter?en_US
dc.typeArticleen_US

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