Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism

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dc.contributor.authorErden, Semih
dc.contributor.authorAkbas Ileri, Betul
dc.contributor.authorSadic Celikkol, Cagla
dc.contributor.authorNalbant, Kevser
dc.contributor.authorKilinc, Ibrahim
dc.contributor.authorYazar, Abdullah
dc.date.accessioned2024-02-23T14:20:33Z
dc.date.available2024-02-23T14:20:33Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractAims To compare vitamin B12, homocysteine, and anti-parietal cell antibody (APCA) levels between children with ASD and controls, paired in terms of age, sex, and socioeconomic level. Methods The research group consisted of 69 children, 36 with ASD and 33 controls. The severity of ASD was determined using the Childhood Autism Rating Scale (CARS). Serum vitamin B12, homocysteine and human anti-parietal cell levels were analysed using enzyme-linked immunosorbent assay. Results The serum vitamin B12 and homocysteine levels in children with ASD were lower than in the control group, but there was no significant difference in terms of APCA levels. Conclusions Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.en_US
dc.description.sponsorshipScientific Research Project Coordination Unit of Necmettin Erbakan University [191218007]en_US
dc.description.sponsorshipFunding for this study was provided by a grant from the Scientific Research Project Coordination Unit of Necmettin Erbakan University [Project no: 191218007].en_US
dc.identifier.doi10.1080/13651501.2021.1906906
dc.identifier.endpage13en_US
dc.identifier.issn1365-1501
dc.identifier.issn1471-1788
dc.identifier.issue1en_US
dc.identifier.pmid33823740en_US
dc.identifier.scopus2-s2.0-85103642045en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage8en_US
dc.identifier.urihttps://doi.org/10.1080/13651501.2021.1906906
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13211
dc.identifier.volume26en_US
dc.identifier.wosWOS:000637270800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal Of Psychiatry In Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutism Spectrum Disorderen_US
dc.subjectChildrenen_US
dc.subjectVitamin B12en_US
dc.subjectHomocysteineen_US
dc.subjectAnti-Parietal Cell Antibodyen_US
dc.titleSerum B12, homocysteine, and anti-parietal cell antibody levels in children with autismen_US
dc.typeArticleen_US

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