Amperometric Glucose Biosensor Based on Glucose Oxidase, 1,10-Phenanthroline-5,6-dione and Carbon Nanotubes

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dc.contributor.authorZor, Erhan
dc.contributor.authorOztekin, Yasemin
dc.contributor.authorRamanaviciene, Almira
dc.contributor.authorAnusevicius, Zilvinas
dc.contributor.authorBingol, Haluk
dc.contributor.authorBarkauskas, Jurgis
dc.contributor.authorErsoz, Mustafa
dc.date.accessioned2024-02-23T14:26:27Z
dc.date.available2024-02-23T14:26:27Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractA biosensor for glucose determination was fabricated by the immobilization of glucose oxidase (GOx) on carbon nanotubes (CNTs) and/or 1,10-phenanthroline-5,6-dione (PD) modified graphite rod electrodes (GOx/PD/CNTs/GR) and its amperometric response toward glucose was investigated under aerobic and anaerobic conditions. The sensitivity of the GOx/PD/CNTs/GR electrode was found to be higher compared to that of a PD-modified GR electrode without CNTs (GOx/PD/GR), implying that CNTs play an important role in the facilitation of electron transfer between the redox active site of GOx and the electrode surface. The GOx/PD/CNTs/GR biosensor exhibited a linear dependency on substrate concentration in a range from 0.0 until 50.0 mM of glucose with oxygen present and from 0.0 until 62.5 mM of glucose in the absence of oxygen. With oxygen present, the limit of detection (LOD) values were determined to be 5.4 and 8.0 mM, and the limit of quantitation values (LOQ) were calculated as 16.2 and 24 mM for GOx/PD/GR and GOx/PD/CNTs/GR, respectively. In the absence of oxygen, the LOD values were calculated as 4.2 and 10.7 mM, and the LOQ values were calculated as 12.6 and 32.1 mM for GOx/PD/GR and GOx/PD/CNTs/GR, respectively. When examining the interference effect of uric acid for GOx/PD/GR and GOx/PD/CNTs/GR electrodes, no significant changes in the amperometric response of the modified electrodes were observed up to 100.0 mM of uric acid. (C) 2014 The Electrochemical Society. All rights reserved.en_US
dc.description.sponsorshipLithuanian Scientific Council [TYR-060]en_US
dc.description.sponsorshipThis work was partially supported by Lithuanian Scientific Council, Project number TYR-060.en_US
dc.identifier.doi10.1149/2.0061413jes
dc.identifier.endpageH3069en_US
dc.identifier.issn0013-4651
dc.identifier.issn1945-7111
dc.identifier.issue13en_US
dc.identifier.scopus2-s2.0-84921267610en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpageH3064en_US
dc.identifier.urihttps://doi.org/10.1149/2.0061413jes
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14198
dc.identifier.volume161en_US
dc.identifier.wosWOS:000345972200012en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElectrochemical Soc Incen_US
dc.relation.ispartofJournal Of The Electrochemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleAmperometric Glucose Biosensor Based on Glucose Oxidase, 1,10-Phenanthroline-5,6-dione and Carbon Nanotubesen_US
dc.typeArticleen_US

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