Determination of optimum time for intravenous cannulation after induction with sevoflurane and nitrous oxide in children premedicated with midazolam

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dc.contributor.authorKilicaslan, Alper
dc.contributor.authorGok, Funda
dc.contributor.authorErol, Atilla
dc.contributor.authorOkesli, Selmin
dc.contributor.authorSarkilar, Gamze
dc.contributor.authorOtelcioglu, Seref
dc.date.accessioned2024-02-23T14:24:34Z
dc.date.available2024-02-23T14:24:34Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackgroundIt has been shown that early placement of an intravenous line in children administered sevoflurane anesthesia increased the incidence of laryngospasm and movement. However, the optimal time for safe cannulation after the loss of the eyelash reflex during the administration of sevoflurane and nitrous oxide is not known. AimThe aim of the study was to determine the optimum time for intravenous cannulation after the induction of anesthesia with sevoflurane and nitrous oxide in children premedicated with oral midazolam. MethodWe performed a prospective, observer-blinded, up-down sequential, allocation study, and children, aged 2-6years, ASA physical status I, scheduled for an elective procedure undergoing inhalational induction were included in the study. Anesthesia was induced with sevoflurane and nitrous oxide after premedication with oral midazolam. For the first child, 4min after the loss of the eyelash reflex, the intravenous cannulation was attempted by an experienced anesthesiologist. The time for intravenous cannulation was considered adequate if movement, coughing, or laryngospasm did not occur. The time for cannulation was increased by 15s if the time was inadequate in the previous patient, and conversely, the time for cannulation was decreased by 15s if the time was adequate in the previous patient. The probit test was used in the analysis of up-down sequences. ResultsA total of 32 children were enrolled sequentially during the study period. The adequate time for effective intravenous cannulation after induction with sevoflurane and nitrous oxide in 50% and 95% of patients were 1.29min (95% confidence interval, 0.96-1.54min) and 1.86min (95% confidence interval 1.58-4.35min), respectively. ConclusionWe recommend waiting 2min for attempting intravenous placement following the loss of the eyelash reflex in children sedated with midazolam and receiving an inhalation induction with sevoflurane and nitrous oxide.en_US
dc.identifier.doi10.1111/pan.12409
dc.identifier.endpage624en_US
dc.identifier.issn1155-5645
dc.identifier.issn1460-9592
dc.identifier.issue6en_US
dc.identifier.pmid24750360en_US
dc.identifier.scopus2-s2.0-84900484955en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage620en_US
dc.identifier.urihttps://doi.org/10.1111/pan.12409
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14012
dc.identifier.volume24en_US
dc.identifier.wosWOS:000335753700011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofPediatric Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChilden_US
dc.subjectSevofluraneen_US
dc.subjectNitrous Oxideen_US
dc.subjectMidazolamen_US
dc.subjectInduction Of Anesthesiaen_US
dc.subjectAdverse Eventsen_US
dc.titleDetermination of optimum time for intravenous cannulation after induction with sevoflurane and nitrous oxide in children premedicated with midazolamen_US
dc.typeArticleen_US

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