The Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016

Basit Öğe Kaydı
dc.contributor.authorHangul, Melih
dc.contributor.authorPekcan, Sevgi
dc.contributor.authorKose, Mehmet
dc.contributor.authorAcican, Deniz
dc.contributor.authorSahlar, Tuba Esra
dc.contributor.authorErdogan, Murat
dc.contributor.authorKendirci, Mustafa
dc.date.accessioned2024-02-23T14:38:03Z
dc.date.available2024-02-23T14:38:03Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractBackground: Cystic fibrosis is the most common metabolic chronic disease among European Caucasian children. Cystic fibrosis incidence in Northern Europeans countries is approximately 1 in 3000 births while the worldwide prevalence varies considerably. Aims: To determine the incidence of cystic fibrosis in the central region of Anatolia in Turkey using the newborn screening program data. Study Design: Cross-sectional study. Methods: We used the records of the newborn screening program which is implemented by the Konya and Kayseri Provincial Health Directories. Between January 2015 and December 2016, there were a total of 119006 live births in Konya and Kayseri. The newborn screening test was applied to all these babies. Results: During this period, there were 22 live born babies diagnosed with cystic fibrosis in Konya with an incidence of 2.9 per 10000 live births and 13 live born babies diagnosed with cystic fibrosis in Kayseri with an incidence of 2.8 per 10000 live births. In genetic of 30 patients, fifteen patients were homozygous, and 15 patients were a compound heterozygote. Twenty-one different gene variants were detected and the most common mutation was F508del (17/30) Conclusion: We found the incidence of cystic fibrosis in central Anatolia similar to northern European countries.en_US
dc.identifier.doi10.4274/balkanmedj.galenos.2018.2018.1332
dc.identifier.endpage183en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue3en_US
dc.identifier.pmid30592194en_US
dc.identifier.scopus2-s2.0-85065831198en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.galenos.2018.2018.1332
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16346
dc.identifier.volume36en_US
dc.identifier.wosWOS:000467416800006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCystic Fibrosisen_US
dc.subjectIncidenceen_US
dc.subjectMiddle Anatoliaen_US
dc.subjectNewborn Screeningen_US
dc.subjectTurkeyen_US
dc.titleThe Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016en_US
dc.typeArticleen_US

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