QT and P-wave dispersions in rheumatic heart disease: Prospective long-term follow up

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dc.contributor.authorAlp, Hayrullah
dc.contributor.authorBaysal, Tamer
dc.contributor.authorAltin, Hakan
dc.contributor.authorKaratas, Zehra
dc.contributor.authorKaraarslan, Sevim
dc.date.accessioned2024-02-23T14:24:35Z
dc.date.available2024-02-23T14:24:35Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackgroundSimple electrocardiogram (ECG) markers have been used to evaluate conduction times. Acute rheumatic fever (ARF) is an autoimmune disease that affects these conduction times. The aim of this prospective long-term follow-up study was to evaluate QT, QTc and P-wave dispersions in children with ARF and chronic rheumatic heart disease (CRHD). MethodsSixty-four patients with ARF, 33 patients with CRHD and 41 healthy, age- and sex-matched control subjects were included in the study. The ARF patients were divided into two subgroups: carditis and arthritis. Echocardiographic and ECG measurements at the onset of diagnosis and final evaluation were included. ResultsQT, QTc and P-wave dispersions were significantly greater in both the ARF carditis and CRHD groups than the ARF arthritis and control subjects during the initial and final analysis (for all, P < 0.001). There was no significant statistical difference in QT, QTc and P-wave dispersion between the initial and final analysis in each groups. Severity of mitral regurgitation and left atrial enlargement were found to be positively correlated with P-wave dispersion (r = 0.438, P < 0.001; r = 0.127, P < 0.001, respectively). QT, QTc and P-wave dispersion greater than 52, 60 and 57 ms, respectively, had higher sensitivity and specificity for predicting ARF carditis. ConclusionThese ECG measurements can be used in the diagnosis of ARF carditis as minor criteria with modified Jones criteria. In contrast, this increase in the dispersions is permanent in patients with ARF carditis.en_US
dc.identifier.doi10.1111/ped.12328
dc.identifier.endpage688en_US
dc.identifier.issn1328-8067
dc.identifier.issn1442-200X
dc.identifier.issue5en_US
dc.identifier.pmid24628726en_US
dc.identifier.scopus2-s2.0-84939260138en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage681en_US
dc.identifier.urihttps://doi.org/10.1111/ped.12328
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14018
dc.identifier.volume56en_US
dc.identifier.wosWOS:000344243200012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChildrenen_US
dc.subjectDiagnosisen_US
dc.subjectDispersionen_US
dc.subjectElectrocardiographic Measurementen_US
dc.subjectRheumatic Valvular Heart Diseaseen_US
dc.titleQT and P-wave dispersions in rheumatic heart disease: Prospective long-term follow upen_US
dc.typeArticleen_US

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