Effects of Rosmarinus officinalis on the survivability of random-patterned skin flaps: An experimental study

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dc.contributor.authorInce, Bilsev
dc.contributor.authorYildirim, Alpagan Mustafa
dc.contributor.authorOkur, Mehmet Ihsan
dc.contributor.authorDadaci, Mehmet
dc.contributor.authorYoruk, Ebru
dc.date.accessioned2024-02-23T14:34:39Z
dc.date.available2024-02-23T14:34:39Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractImproving survival of skin flaps used in soft-tissue reconstruction is clinically an important goal, and several systemic and local agents have been used for this purpose. However, a substance that prevents the flap necrosis has not yet been defined. This study aimed to investigate whether a Rosmarinus officinalis extract could improve the skin flap survival. In this study, 21 Wistar albino rats were divided into three groups. Rectangular 8 x 2 cm random-pattern flaps were elevated from the back of the rats. Group I was considered the control group. In Group II, a 0.5-cc of Rosmarinus officinalis oil was applied with an ear bud to the flap area 30 minutes before the flap elevation. After suturing the flaps to their location, the oil was administered twice a day for a week. In Group III, 0.5 cc of the oil was applied twice a day to the area that was elevated for a week until surgery. At the end of the week, the flaps were sutured to their location, and wiped postoperatively twice a day for a week with the oil. Mean percentage of these areas was found to be 29.81%, 58.99%, and 67.68% in Group I, Group II, and Group III, respectively. The mean percentage of the flap survival areas and vessel diameters were significantly greater in the Groups II and III than in the control group (p < 0.05). The results revealed that the topical use of the Rosmarinus officinalis extract can increase the flap survivability.en_US
dc.identifier.doi10.3109/2000656X.2014.907172
dc.identifier.endpage87en_US
dc.identifier.issn2000-656X
dc.identifier.issn2000-6764
dc.identifier.issue2en_US
dc.identifier.pmid24702647en_US
dc.identifier.scopus2-s2.0-84924675009en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.3109/2000656X.2014.907172
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15691
dc.identifier.volume49en_US
dc.identifier.wosWOS:000351350700004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Plastic Surgery And Hand Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTissue Defecten_US
dc.subjectRepairen_US
dc.subjectRosmarinus Officinalisen_US
dc.subjectFlap Survivabilityen_US
dc.titleEffects of Rosmarinus officinalis on the survivability of random-patterned skin flaps: An experimental studyen_US
dc.typeArticleen_US

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