NEUTROPHIL-LYMPHOCYTE RATIO IN PATIENTS WITH PESTICIDE POISONING

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dc.contributor.authorDundar, Zerrin Defne
dc.contributor.authorErgin, Mehmet
dc.contributor.authorKoylu, Ramazan
dc.contributor.authorOzer, Rasit
dc.contributor.authorCander, Basar
dc.contributor.authorGunaydin, Yahya Kemal
dc.date.accessioned2024-02-23T14:12:47Z
dc.date.available2024-02-23T14:12:47Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackground: Pesticides are highly toxic to human beings, and pesticide poisoning is associated with high morbidity and mortality. The identification of powerful prognostic markers is important for the management of patients with pesticide poisoning in emergency settings. Objective: To investigate the prognostic value of the neutrophil-lymphocyte ratio and hematological parameters measured in patients with pesticide poisoning within the first 24 h after admission to the emergency department (ED). Methods: All patients (>= 15 years old) admitted to the ED from July 2008 through February 2013 due to pesticide poisoning were enrolled in the study. The written and electronic medical charts of patients were reviewed. Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were calculated for each patient using absolute neutrophil, lymphocyte, and platelet counts. Mechanical ventilation requirement and mortality were used as the primary endpoints. Results: A total of 189 patients were included in the study. The mechanically ventilated patients had significantly higher leukocyte and neutrophil counts, and neutrophil-lymphocyte and platelet-lymphocyte ratios (p < 0.001, p < 0.001, p < 0.001, p = 0.003, respectively), whereas they had significantly lower lymphocyte counts compared to nonventilated patients (p = 0.011). Survivors had significantly higher leukocyte and neutrophil counts, and neutrophil-lymphocyte ratios (p < 0.001, p < 0.001, p = 0.002, respectively), whereas there was no significant difference between groups in terms of lymphocyte counts (p = 0.463), compared to nonsurvivors. Conclusion: Leukocyte counts, neutrophil counts, and neutrophil-lymphocyte ratios measured within the first 24 h after admission to the ED are useful and easy-to-use parameters for estimating prognosis in the follow-up of patients with pesticide poisoning. (C) 2014 Elsevier Inc.en_US
dc.identifier.doi10.1016/j.jemermed.2014.01.034
dc.identifier.endpage293en_US
dc.identifier.issn0736-4679
dc.identifier.issn1090-1280
dc.identifier.issue3en_US
dc.identifier.pmid24958695en_US
dc.identifier.scopus2-s2.0-84906935865en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://doi.org/10.1016/j.jemermed.2014.01.034
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12180
dc.identifier.volume47en_US
dc.identifier.wosWOS:000341443300014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofJournal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPesticideen_US
dc.subjectPoisoningen_US
dc.subjectCholinesteraseen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.titleNEUTROPHIL-LYMPHOCYTE RATIO IN PATIENTS WITH PESTICIDE POISONINGen_US
dc.typeArticleen_US

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