The evaluation of cochlear functions in Familial Mediterranean Fever

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dc.contributor.authorEryilmaz, Mehmet Akif
dc.contributor.authorYucel, Abitter
dc.contributor.authorCure, Erkan
dc.contributor.authorSakiz, Davut
dc.contributor.authorKoder, Ahmet
dc.contributor.authorKucuk, Adem
dc.contributor.authorTunc, Recep
dc.date.accessioned2024-02-23T13:43:48Z
dc.date.available2024-02-23T13:43:48Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractFamilial Mediterranean Fever (FMF) is a progressive disease characterized by chronic inflammation, which also has negative effects on cochlear functions and hearing levels. We investigated whether the cochlear functions and hearing levels of FMF patients were different than healthy controls and also evaluated the relationship of hearing levels with the age at diagnosis, duration without treatment, and inflammation and lipid parameters in this study. A total of 60 patients diagnosed with FMF and 48 age, gender and body mass index (BMI)-matched healthy controls were included in the study. The hemogram, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and lipid parameters of the subjects were studied and they all underwent pure tone audiometry and Transient evoked otoacoustic emission tests after an otologic examination. The hearing levels of the FMF group were significantly higher than those of the control group. The TEOAE signal/noise (S/N) ratios were similar in both groups. A positive relationship was present between the audiometric test results and the age, BMI, low-density lipoprotein and triglyceride levels and a negative relationship with the high-density lipoprotein levels. A negative relationship was present between the TEOAE S/N ratios and the age of the patients, duration without treatment, lipid parameters, inflammation markers and the creatinine level. FMF patients are exposed to chronic inflammation and this can influence their hearing levels. The age at diagnosis, duration without treatment, chronic inflammation, unfavorable lipid parameters, and obesity can affect hearing tests negatively.en_US
dc.identifier.doi10.1007/s00405-016-4067-5
dc.identifier.endpage4126en_US
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue12en_US
dc.identifier.pmid27130205en_US
dc.identifier.scopus2-s2.0-84964612445en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage4119en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-016-4067-5
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10929
dc.identifier.volume273en_US
dc.identifier.wosWOS:000387700400008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFamilial Mediterranean Feveren_US
dc.subjectTransient Evoked Otoacoustic Emission Testen_US
dc.subjectPure Tone Audiometryen_US
dc.subjectCochlear Involvementen_US
dc.titleThe evaluation of cochlear functions in Familial Mediterranean Feveren_US
dc.typeArticleen_US

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