Visceral Adiposity Index Levels in Patients with Hypothyroidism

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dc.contributor.authorPekgor, Selma
dc.contributor.authorDuran, Cevdet
dc.contributor.authorKutlu, Ruhusen
dc.contributor.authorSolak, Ibrahim
dc.contributor.authorPekgor, Ahmet
dc.contributor.authorEryilmaz, Mehmet Ali
dc.date.accessioned2024-02-23T14:12:53Z
dc.date.available2024-02-23T14:12:53Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractObjective: To assess visceral adiposity index (VAI) as a sign of cardio-vascular diseases (CVD) in hypothyroidism patients and to compare CVD risks in overt or subclinical hypothyroidism patients. Materials and methods: Sixty-eight hypothyroidism patients (29 with overt and 39 with subclinical hypothyroidism) and 33 age- and gender-matched control patients were included. VAI levels were calculated with the following formula: (waist circumference (WC)/[36.58+(1.89xbody mass index (BMI))])x[(triglyceride (TG) (mmol/L)/0.81)x(1.52xhigh-density lipoprotein cholesterol (HDL-cholesterol) (mmol/L))] and (WC/[39.68+(1.88xBMI)])x[(TG (mmol/L)/1.03)x(1.31xHDL-cholesterol (mmol/L))], respectively. Results: While body weight (p < 0.01), BMI (p < 0.01), TG and VAI levels (p < 0.01) were higher in hypothyroidism patients than controls, HDL-cholesterol levels were lower (p = 0.02). When patients were divided to groups as subclinical (n = 39) and overt hypothyroidism (n = 29) and compared with each other and controls (n = 33), body weight (p = 0.02 and p = 0.02, respectively), BMI (p = 0.01 and p < 0.01, respectively) and TG (p < 0.01 and p = 0.03, respectively) were higher in overt and subclinical hypothyroidism groups than controls. HDL-cholesterol was lower only in the group with overt hypothyroidism than controls (p = 0.01). Although found similar to each other in overt and subclinical hypothyroidism groups, VAI levels were observed to be higher in both groups than controls (p < 0.01 and p = 0.02, respectively). In correlation analysis, a positive correlation was determined between thyroid stimulating hormone (TSH), BMI and VAI levels (p = 0.03 and p < 0.01, respectively). Conclusions: Due to the association between increased VAI levels, and metabolic syndrome and CVDs, we consider that several measures should be promptly taken to decrease these risk factors, and further studies with a larger sample size should be performed.en_US
dc.description.sponsorshipKonya Training and Research Hospitalen_US
dc.description.sponsorshipThe study was supported by the research fund of Konya Training and Research Hospital.en_US
dc.identifier.doi10.1016/j.jnma.2018.03.009
dc.identifier.endpage613en_US
dc.identifier.issn0027-9684
dc.identifier.issn1943-4693
dc.identifier.issue6en_US
dc.identifier.pmid30129492en_US
dc.identifier.scopus2-s2.0-85045714835en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage606en_US
dc.identifier.urihttps://doi.org/10.1016/j.jnma.2018.03.009
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12228
dc.identifier.volume110en_US
dc.identifier.wosWOS:000450091500017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNatl Med Assocen_US
dc.relation.ispartofJournal Of The National Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHypothyroidismen_US
dc.subjectOvert Hypothyroidismen_US
dc.subjectSubclinical Hypothyroidismen_US
dc.subjectVisceral Adiposity Indexen_US
dc.subjectCardiovascular Risken_US
dc.titleVisceral Adiposity Index Levels in Patients with Hypothyroidismen_US
dc.typeArticleen_US

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