Evaluation of echocardiographic indices for the prediction of major adverse events during long-term follow-up in chronic hemodialysis patients with normal left ventricular ejection fraction

Basit Öğe Kaydı
dc.contributor.authorDogan, U.
dc.contributor.authorOzdemir, K.
dc.contributor.authorAkilli, H.
dc.contributor.authorAribas, A.
dc.contributor.authorTurk, S.
dc.date.accessioned2024-02-23T14:45:34Z
dc.date.available2024-02-23T14:45:34Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractBackground: Cardiovascular disease is the leading cause of mortality in end-stage renal failure. Prognostic role of echocardiography has not been fully elucidated in chronic hemodialysis patients. Aim: To assess the ability of Doppler echocardiographic parameters of left ventricular (LV) diastolic function along with conventional echocardiographic indices to predict long-term adverse major events in chronic hemodialysis patients with normal LV ejection fraction (EF). Patients and Methods: A total of 45 chronic hemodialysis patients (aged 49 15 years) were included to the study. All patients underwent complete standard and tissue Doppler imaging echocardiography before and immediately after hemodialysis session and were followed-up prospectively. Major outcome measure was the combination of all-cause death and hospitalization for any cardiovascular event. Results: During the follow up period (52 +/- 26 months) 23 major events occured (17 all-cause deaths and 6 cardiovascular events requring hospitalization). Post-dialytic values of mean left atrial diameter, mitral E (peak early mitral inflow velocity), E/Vp [ratio of mitral E to flow propagation velocity (Vp)] and E/Ea [ratio of mitral E to peak early diastolic mitral annular velocity (Ea)] (average of 4 segments of mitral annulus) were significantly higher in patients who had major events. In Cox proportional hazard analysis only E/Ea ratio predicted combined endpoint of all-cause mortality and nonfatal cardiovascular events (hazard ratio: 1.20; confidence interval: 1.03-1.39; p=0.018). The optimum cut-off value for E/Ea determined by ROC curve analysis revealed that E/Ea ratio higher than 9.8 predicted future events with sensitivity of 74% and specificity of 86%. Conclusions: E/Ea might be an accurate echocardiographic indice during long-term follow up for the prediction of major adverse events in chronic hemodialysis patients with normal LV EF.en_US
dc.identifier.endpage324en_US
dc.identifier.issn1128-3602
dc.identifier.issue3en_US
dc.identifier.pmid22530347en_US
dc.identifier.scopus2-s2.0-84859922218en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage316en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17511
dc.identifier.volume16en_US
dc.identifier.wosWOS:000302849100005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdverse Eventsen_US
dc.subjectCardiovascular Outcomesen_US
dc.subjectDoppleren_US
dc.subjectEchocardiographyen_US
dc.subjectHemodialysisen_US
dc.titleEvaluation of echocardiographic indices for the prediction of major adverse events during long-term follow-up in chronic hemodialysis patients with normal left ventricular ejection fractionen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu