A Case of Nodular Cystic Acne Treated with Systemic Dapsone

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dc.contributor.authorDaye, Munise
dc.contributor.authorTemiz, Selami Aykut
dc.date.accessioned2024-02-23T14:38:09Z
dc.date.available2024-02-23T14:38:09Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractDapsone is an aniline derivative from synthetic sulfones. The mechanism of action of dapsone is obscure in inflammatory diseases; however, it is suggested to inhibit neutrophil chemotaxis and lysosomal enzymes. Acne vulgaris (AV) is a chronic inflammatory disorder of the pilo-sebaceous unit. Herein we report a pediatric patient who was started systemic isotretionin due to severe nodular cystic AV but could not continue due to elevated liver enzymes and well response to systemic dapsone treatment. We consider that per-oral dapsone treatment may be a well-tolerated and effective treatment option in patients with moderate/severe, frequently recurring AV which is irresponsive to conventional therapies and may a good alternative to isotretionin particularly in pediatric cases.en_US
dc.identifier.doi10.4274/jarem.galenos.2019.2444
dc.identifier.endpage105en_US
dc.identifier.issn2146-6505
dc.identifier.issn2147-1894
dc.identifier.issue1en_US
dc.identifier.startpage103en_US
dc.identifier.urihttps://doi.org/10.4274/jarem.galenos.2019.2444
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16384
dc.identifier.volume10en_US
dc.identifier.wosWOS:000530895000020en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of Academic Research In Medicine-Jaremen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDapsoneen_US
dc.subjectIsotretinoinen_US
dc.subjectNodulocytic Acneen_US
dc.titleA Case of Nodular Cystic Acne Treated with Systemic Dapsoneen_US
dc.typeArticleen_US

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