The role of the BUN/albumin ratio in predicting mortality in COVID-19 patients in the emergency department

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dc.contributor.authorKucukceran, Kadir
dc.contributor.authorAyranci, Mustafa Kursat
dc.contributor.authorGirisgin, Abdullah Sadik
dc.contributor.authorKocak, Sedat
dc.contributor.authorDundar, Zerrin Defne
dc.date.accessioned2024-02-23T14:02:03Z
dc.date.available2024-02-23T14:02:03Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractIntroduction: Due to the high mortality and spread rates of coronavirus disease 2019 (COVID-19), there are currently serious challenges in emergency department management. As such, we investigated whether the blood urea nitrogen (BUN)/albumin ratio (BAR) predicts mortality in the COVID-19 patients in the emergency department. Methods: A total of 602 COVID-19 patients who were brought to the emergency department within the period from March to September 2020 were included in the study. The BUN level, albumin level, BAR, age, gender, and in-hospital mortality status of the patients were recorded. The patients were grouped by in-hospital mortality. Statistical comparison was conducted between the groups. Results: Of the patients who were included in the study, 312(51.8%) were male, and their median age was 63 years (49-73). There was in-hospital mortality in 96(15.9%) patients. The median BUN and BAR values of the patients in the non-survivor group were significantly higher than those in the survivor group (BUN: 24.76 [17.38-38.31] and 14.43 [10.84-20.42], respectively [p < 0.001]; BAR: 6.7 [4.7-10.1] and 3.4 [2.5-5.2], respectively [p < 0.001]). The mean albumin value in the non-survivor group was significantly lower than that in the survivor group (3.60 +/- 0.58 and 4.13 +/- 0.51, respectively; p < 0.001). The area-under-the-curve (AUC) and odds ratio values obtained by BAR to predict in-hospital COVID-19 mortality were higher than the values obtained by BUN and albumin (AUC of BAR, BUN, and albumin: 0.809, 0.771, and 0.765, respectively; odds ratio of BAR>3.9, BUN>16.05, and albumin<4.01: 10.448, 7.048, and 6.482, respectively). Conclusion: The BUN, albumin, and BAR levels were found to be reliable predictors of in-hospital mortality in COVID-19 patients, but BAR was found to be a more reliable predictor than the BUN and albumin levels. (c) 2021 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2021.03.090
dc.identifier.endpage37en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.pmid33838471en_US
dc.identifier.scopus2-s2.0-85103714321en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2021.03.090
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11553
dc.identifier.volume48en_US
dc.identifier.wosWOS:000701895500005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCovid-19en_US
dc.subjectBlood Urea Nitrogenen_US
dc.subjectSerum Albuminen_US
dc.subjectIn-Hospital Mortalityen_US
dc.titleThe role of the BUN/albumin ratio in predicting mortality in COVID-19 patients in the emergency departmenten_US
dc.typeArticleen_US

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