Magnetic Resonance Imaging May Be a Valuable Radiation-Free Technique for Lung Pathologies in Patients with Primary Immunodeficiency

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dc.contributor.authorArslan, Sevket
dc.contributor.authorPoyraz, Necdet
dc.contributor.authorUcar, Ramazan
dc.contributor.authorYesildag, Mihrican
dc.contributor.authorYesildag, Ahmet
dc.contributor.authorCaliskaner, Ahmet Zafer
dc.date.accessioned2024-02-23T13:56:14Z
dc.date.available2024-02-23T13:56:14Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractPurpose In some primary immunodeficiency (PID) patients, especially in the subgroup with common variable immunodeficiency (CVID), radiosensitivity is a concern and avoidance of repeated radiation exposure has been recommended. To investigate the use of lung Magnetic resonance imaging (MRI) instead of Computed Tomography (CT) for the diagnosis and follow-up of various lesions in the lung parenchyma and airways, especially in PID patients in whom x-ray exposure should be limited. Methods The study enrolled 23 patients with PID who underwent thorax CT within the last 3 months and/or who will undergo initial radiological assessment. Lung MRI was performed in all patients to compare the pulmonary findings with CT images. Results MRI performance was weaker at detecting bronchiectasis extension, and a low concordance was found between MRI and CT in the assessment of the number of bronchial generations. CT better identified peripheral airway abnormalities, while CT and MRI gave similar results for detecting the presence and extension of consolidation, bullae, mucus plugging, bronchial wall thickening, bronchiectasis severity and nodules. Conclusions Despite the low spatial resolution, higher cost, and low availability, we suggest MRI as a possible radiation-free alternative to CT in selected patients with PID.en_US
dc.identifier.doi10.1007/s10875-015-0227-4
dc.identifier.endpage72en_US
dc.identifier.issn0271-9142
dc.identifier.issn1573-2592
dc.identifier.issue1en_US
dc.identifier.pmid26707785en_US
dc.identifier.scopus2-s2.0-84958160286en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage66en_US
dc.identifier.urihttps://doi.org/10.1007/s10875-015-0227-4
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11141
dc.identifier.volume36en_US
dc.identifier.wosWOS:000368726600012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer/Plenum Publishersen_US
dc.relation.ispartofJournal Of Clinical Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPrimary Immunodeficiencyen_US
dc.subjectRadiosensitivityen_US
dc.subjectLung Imagingen_US
dc.subjectComputerized Tomographyen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.titleMagnetic Resonance Imaging May Be a Valuable Radiation-Free Technique for Lung Pathologies in Patients with Primary Immunodeficiencyen_US
dc.typeArticleen_US

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