Management of Large Oroantral Fistulas Caused by Medication-Related Osteonecrosis with the Combined Sequestrectomy, Buccal Fat Pad Flap and Platelet-Rich Fibrin

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dc.contributor.authorEsen, Alparslan
dc.contributor.authorAkkulah, Sebnem
dc.date.accessioned2024-02-23T13:59:57Z
dc.date.available2024-02-23T13:59:57Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractPurpose The aim of this retrospective study was to describe the efficacy of management of bisphosphonate-related maxillary osteonecrosis, which had resulted in an oroantral fistula formation, by performing sequestrectomy, platelet-rich fibrin (PRF) and buccal fat pad (BFP) flap. Patient and Methods A total of 7 patients diagnosed with stage III maxillary medication-related osteonecrosis according to guidelines of the American Association of Oral and Maxillofacial Surgeons. All patients complained of persistent pain, swelling and purulent drainage with sinusitis. In order to keep the infection under control, the patients first received an antibiotic combination for 2 weeks. Then, sequestrectomy and bone debridement were performed under general anesthesia. After that, an antrectomy was performed via endoscopic sinus surgery in some cases. And the fistula was closed with BFP after or before the PRF application to the region depending on the size of the fistula. Results The fistula was successfully closed. After a mean follow-up of 16 months, no symptoms were seen in the patients. Conclusions The patients were successfully managed with a combined treatment consisted of sequestrectomy, PRF and BFP. We suggest that large defects arose from medication-related osteonecrosis of the jaw can be managed with such a combined approach in order to lessen the recurrence risk.en_US
dc.identifier.doi10.1007/s12663-019-01278-x
dc.identifier.endpage82en_US
dc.identifier.issn0972-8279
dc.identifier.issn0974-942X
dc.identifier.issue1en_US
dc.identifier.pmid33584046en_US
dc.identifier.scopus2-s2.0-85074020957en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage76en_US
dc.identifier.urihttps://doi.org/10.1007/s12663-019-01278-x
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11394
dc.identifier.volume20en_US
dc.identifier.wosWOS:000614074900012en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofJournal Of Maxillofacial & Oral Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMedication-Related Osteonecrosis Of The Jawen_US
dc.subjectBisphosphonatesen_US
dc.subjectOroantral Fistulaen_US
dc.subjectSequestrectomyen_US
dc.subjectBuccal Fat Paden_US
dc.subjectPlatelet-Rich Fibrinen_US
dc.titleManagement of Large Oroantral Fistulas Caused by Medication-Related Osteonecrosis with the Combined Sequestrectomy, Buccal Fat Pad Flap and Platelet-Rich Fibrinen_US
dc.typeArticleen_US

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