Discriminative sensing of DOPA enantiomers by cyclodextrin anchored graphene nanohybrids

Basit Öğe Kaydı
dc.contributor.authorAtes, Salih
dc.contributor.authorZor, Erhan
dc.contributor.authorAkin, Ilker
dc.contributor.authorBingol, Haluk
dc.contributor.authorAlpaydin, Sabri
dc.contributor.authorAkgemci, Emine G.
dc.date.accessioned2024-02-23T14:00:16Z
dc.date.available2024-02-23T14:00:16Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractDiscriminative sensing of chiral species with a convenient and robust system is a challenge in chemistry, pharmaceutics and particularly in biomedical science. Advanced nanohybrid materials for discrimination of these biologically active molecules can be developed by combination of individual obvious advantages of different molecular scaffolds. Herein, we report on the comparison of the performance of cyclodextrin functionalized graphene derivatives (x-CD/rGO, x: alpha-, beta-, gamma-) for discrimination of DOPA enantiomers. Within this respect, electrochemical measurements were conducted and the experimental results were compared to molecular docking method. Thanks to cavity size of g-CD and the unique properties of graphene, rGO/gamma-CD nanohybrid is capable of selective recognition of DOPA enantiomers. Limit of detection (LOD) value and sensitivity were determined as 15.9 mu M and 0.2525 mu A mu M-1 for D- DOPA, and 14.9 mu M and 0.6894 mu A mu M-1 for L-DOPA. (C) 2017 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [113Z664]en_US
dc.description.sponsorshipWe express our deep thanks to the Scientific and Technological Research Council of Turkey (TUBITAK) for financial support (113Z664).en_US
dc.identifier.doi10.1016/j.aca.2017.03.052
dc.identifier.endpage37en_US
dc.identifier.issn0003-2670
dc.identifier.issn1873-4324
dc.identifier.pmid28433056en_US
dc.identifier.scopus2-s2.0-85017399995en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage30en_US
dc.identifier.urihttps://doi.org/10.1016/j.aca.2017.03.052
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11533
dc.identifier.volume970en_US
dc.identifier.wosWOS:000399781700003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofAnalytica Chimica Actaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGraphene Nanohybriden_US
dc.subjectDopaen_US
dc.subjectEnantioselective Sensoren_US
dc.subjectDiscriminationen_US
dc.subjectVoltammetryen_US
dc.titleDiscriminative sensing of DOPA enantiomers by cyclodextrin anchored graphene nanohybridsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu