Percentages of serum, liver and adipose tissue fatty acids and body weight are affected in female rats by long-term Central kisspeptin treatments

Basit Öğe Kaydı
dc.contributor.authorSahin, Zafer
dc.contributor.authorOzcan, Mete
dc.contributor.authorOzkaya, Ahmet
dc.contributor.authorCanpolat, Sinan
dc.contributor.authorKutlu, Selim
dc.contributor.authorKelestimur, Haluk
dc.date.accessioned2024-02-23T14:20:34Z
dc.date.available2024-02-23T14:20:34Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractThis study was conducted to determine the possible effects of long-term exogenous kisspeptin and its antagonist P234 on serum, liver and adipose tissue fatty acids (FA) profiles, as well as body weight, in female rats. Kisspeptin (50 pmol) and P234 (1 nmol) were administrated to the weaned Sprague-Dawley female rats by an intracerebroventricular injection from the 26th postnatal day to the 60th postnatal day. Percentages of the serum total saturated FA ( n-ary sumation SFA) and total monounsaturated FA ( n-ary sumation MUFA) were lower in the kisspeptin group. In the adipose tissue, n-ary sumation SFA was lower and total unsaturated FA higher in the P234 group. Moreover, long-term central kisspeptin injection caused a decrease in the body weight. When compared to the kisspeptin group, the final body weights were higher in the P234 and kisspeptin + P234 groups. According to our results, we suggest that kisspeptin has a regulatory role in FA metabolism and regulation of body weight.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey [TUBITAK] [113S193]en_US
dc.description.sponsorshipThis study was supported by the Scientific and Technological Research Council of Turkey [TUBITAK, Project no: 113S193].en_US
dc.identifier.doi10.1080/13813455.2020.1819339
dc.identifier.endpage315en_US
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.issue2en_US
dc.identifier.pmid32951481en_US
dc.identifier.scopus2-s2.0-85091177279en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage307en_US
dc.identifier.urihttps://doi.org/10.1080/13813455.2020.1819339
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13218
dc.identifier.volume129en_US
dc.identifier.wosWOS:000571304400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArchives Of Physiology And Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKisspeptinen_US
dc.subjectKisspeptin Antagonisten_US
dc.subjectFatty Acidsen_US
dc.subjectBody Weighten_US
dc.subjectEnergy Metabolismen_US
dc.subjectRaten_US
dc.titlePercentages of serum, liver and adipose tissue fatty acids and body weight are affected in female rats by long-term Central kisspeptin treatmentsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu