Changes in the Serum Levels of Trace Elements Before and After the Operation in Thyroid Cancer Patients

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dc.contributor.authorBaltaci, Abdulkerim Kasim
dc.contributor.authorDundar, Tugrul Kadir
dc.contributor.authorAksoy, Faruk
dc.contributor.authorMogulkoc, Rasim
dc.date.accessioned2024-02-23T13:59:43Z
dc.date.available2024-02-23T13:59:43Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractThe present study aims to examine the changes in the serum levels of trace elements before and after the operation in thyroid cancer patients. The study registered 50 individuals, of whom 25 were female and 25 were male. The patients were allocated to four groups: group 1: male thyroid cancer patients group (n = 15), group 2: female thyroid cancer patients group (n = 15), group 3: male control group (n = 10), group 4: female control group (n = 10). The subjects in groups 1 and 2 were the patients who were post-operatively diagnosed with a pathological malignancy in the thyroid tissue samples. Blood samples were collected from all subjects before the operation, immediately after the operation, and on the post-operative day 15. Additionally, thyroid tissue samples were taken from all subjects post-operatively. Some elements in the blood and tissue samples were determined using the atomic emission method. Zinc and selenium levels of groups 1 and 2 in the pre- and post-operative measurements were significantly lower than those in the control groups (p < 0.05), but were higher in the thyroid tissue (p < 0.05). Serum zinc and selenium levels measured in the subjects on the post-operative day 15 were similar to those measured in the controls. Our study show that changes in the serum and thyroid tissue levels of trace elements like zinc and selenium, which play a critical role in thyroid function, might be associated with the pathogenesis of thyroid cancer.en_US
dc.description.sponsorshipScientific Research Projects Coordinatorship of Selcuk University (SUBAPK) [09202081]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Coordinatorship of Selcuk University (SUBAPK; project no. 09202081).en_US
dc.identifier.doi10.1007/s12011-016-0768-2
dc.identifier.endpage64en_US
dc.identifier.issn0163-4984
dc.identifier.issn1559-0720
dc.identifier.issue1en_US
dc.identifier.pmid27263537en_US
dc.identifier.scopus2-s2.0-85008208885en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://doi.org/10.1007/s12011-016-0768-2
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11291
dc.identifier.volume175en_US
dc.identifier.wosWOS:000392194700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofBiological Trace Element Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThyroid Canceren_US
dc.subjectZincen_US
dc.subjectSeleniumen_US
dc.subjectCopperen_US
dc.subjectIronen_US
dc.titleChanges in the Serum Levels of Trace Elements Before and After the Operation in Thyroid Cancer Patientsen_US
dc.typeArticleen_US

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