Effects of non-surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trial

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dc.contributor.authorYarkac, Fatma Ucan
dc.contributor.authorOgrum, Atiye
dc.contributor.authorGokturk, Ozge
dc.date.accessioned2024-02-23T14:24:21Z
dc.date.available2024-02-23T14:24:21Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractAim The purpose of this randomized controlled clinical study was to evaluate the effect of non-surgical mechanical periodontal therapy on the inflammatory status and severity of psoriasis in subjects with psoriasis. Material and methods The study population consisted of 92 periodontitis patients with psoriasis vulgaris suffering from an untreated periodontal disease. Two randomized groups were formed from these patients: immediate periodontal therapy (test group, n = 46) and delayed periodontal therapy (control group, n = 46). Periodontal clinical measures, on salivary interleukin 2, interleukin 6 and secretory immunoglobulin A levels and the Psoriasis Area and Severity Index (PASI) scores were evaluated at baseline and on the 8th week in control and test groups. Results Eight weeks after completion of non-surgical periodontal therapy (test group) or initial examination (control group), a significant decrease was observed in interleukin 2, interleukin 6 level and in PASI score, whereas a significant increase was observed in secretory immunoglobulin A levels in the test group (p < .05). Conclusion Within the limits of this study, the results suggest that effective periodontal therapy improves the psoriasis condition in patients afflicted by both diseases.en_US
dc.identifier.doi10.1111/jcpe.13205
dc.identifier.endpage201en_US
dc.identifier.issn0303-6979
dc.identifier.issn1600-051X
dc.identifier.issue2en_US
dc.identifier.pmid31571243en_US
dc.identifier.scopus2-s2.0-85076392581en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage193en_US
dc.identifier.urihttps://doi.org/10.1111/jcpe.13205
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13923
dc.identifier.volume47en_US
dc.identifier.wosWOS:000498506400001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Clinical Periodontologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImmunoglobulin Aen_US
dc.subjectInterleukin-2en_US
dc.subjectInterleukin-6en_US
dc.subjectPeriodontal Diseasesen_US
dc.subjectPsoriasis Vulgarisen_US
dc.titleEffects of non-surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trialen_US
dc.typeArticleen_US

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