Systemic Atopy and Immunoglobulin Deficiency in Turkish Patients with Vernal Keratoconjunctivitis

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dc.contributor.authorBozkurt, Banu
dc.contributor.authorArtac, Hasibe
dc.contributor.authorArslan, Nasha
dc.contributor.authorGokturk, Bahar
dc.contributor.authorBozkurt, Mete Kaan
dc.contributor.authorReisli, Ismail
dc.contributor.authorIrkec, Murat
dc.date.accessioned2024-02-23T14:34:37Z
dc.date.available2024-02-23T14:34:37Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractPurpose: To determine the prevalence of systemic atopy and immunoglobulin (Ig) deficiencies in vernal keratoconjunctivitis (VKC). Methods: Sixty-seven VKC subjects (79.1% boys) with a mean age of 11.3 +/- 4.3 years were included. Serum Ig levels and specific IgE levels were measured using the nephelometric method and reversed enzyme immunoassay with sandwich ELISA technique, respectively. The patients underwent epidermal skin tests with commercial extracts. Results: Family history of atopy and associated systemic allergies were detected in 32.8 and 40.3% of the subjects, respectively. Blood eosinophilia, elevated total, and specific IgE and positive skin tests were detected in 33.8, 42.2, 50, and 35% of the subjects, respectively. Out of 62 subjects, low levels of IgA, IgG, IgM, and IgG3 were detected in 12.9, 8, 6.5, and 1.6% of the patients, respectively. Conclusion: IgE-mediated mechanisms are involved in approximately 40% of VKC patients. A new finding was the higher incidence of Ig deficiency.en_US
dc.identifier.doi10.3109/09273948.2012.723110
dc.identifier.endpage26en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue1en_US
dc.identifier.pmid23323578en_US
dc.identifier.scopus2-s2.0-84872320659en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://doi.org/10.3109/09273948.2012.723110
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15665
dc.identifier.volume21en_US
dc.identifier.wosWOS:000313682500005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology And Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergic Sensitizationen_US
dc.subjectImmunoglobulin Deficiencyen_US
dc.subjectSerum Specific Ige Levelen_US
dc.subjectSkin Prick Testsen_US
dc.subjectVernal Keratoconjunctivitisen_US
dc.titleSystemic Atopy and Immunoglobulin Deficiency in Turkish Patients with Vernal Keratoconjunctivitisen_US
dc.typeArticleen_US

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