Two cases of gastrointestinal stromal tumor of the small intestine with liver and bone metastasis

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dc.contributor.authorAktan, Meryem
dc.contributor.authorKoc, Mehmet
dc.contributor.authorYavuz, Berrin Benli
dc.contributor.authorKanyilmaz, Gul
dc.date.accessioned2024-02-23T14:37:37Z
dc.date.available2024-02-23T14:37:37Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractGastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. These tumors most commonly occur in the stomach (60%), jejunum and ileum (30%). Metastasis is characteristically the malignant behavior of the GISTs. GISTs most frequently metastasize to the liver and peritoneum, whereas bone and lung metastases are uncommon sites. Here, we described two cases of bone and liver metastases in patients with advanced GISTs. Both of them showed liver metastasis at disease presentation and bone metastasis in early time after the diagnosis. Bone metastases involved the lumber spine and right femur in first patient and L2 vertebral body in the second case. All of the lesions presented a lytic pattern. These cases are presented because of the rare incidence of bone metastasis to femur and vertebral bodies. More attention should be paid to the diagnosis of bone metastases from GISTs in clinical practice despite the shortage of available data on the sensitivity and specificity of bone scintigraphy and PET-CT.en_US
dc.identifier.doi10.3978/j.issn.2305-5839.2015.09.46
dc.identifier.issn2305-5839
dc.identifier.issn2305-5847
dc.identifier.issue17en_US
dc.identifier.pmid26605305en_US
dc.identifier.scopus2-s2.0-85015482066en_US
dc.identifier.urihttps://doi.org/10.3978/j.issn.2305-5839.2015.09.46
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16149
dc.identifier.volume3en_US
dc.identifier.wosWOS:000421420700018en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAme Publ Coen_US
dc.relation.ispartofAnnals Of Translational Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastrointestinal Stromal Tumor (Gist)en_US
dc.subjectBoneen_US
dc.subjectMetastasisen_US
dc.titleTwo cases of gastrointestinal stromal tumor of the small intestine with liver and bone metastasisen_US
dc.typeArticleen_US

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