Reactivation of Tuberculosis and COVID-19 in Pediatric Patients

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dc.contributor.authorUnal, Gokcen
dc.contributor.authorPekcan, Sevgi
dc.contributor.authorAkcan, Ozge Metin
dc.contributor.authorKeles, Sevgi
dc.contributor.authorYilmaz, Asli Imran
dc.contributor.authorEldeniz, Fadime Ceyda
dc.contributor.authorCaglar, Hanife Tugce
dc.date.accessioned2024-02-23T14:17:01Z
dc.date.available2024-02-23T14:17:01Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractObjective Mycobacterium tuberculosis is an immobile aerobic bacillus that causes tuberculosis (TB) disease. We aimed to evaluate the association between coronavirus disease 2019 (COVID-19), COVID-19-related drugs, TB reactivation, and TB incidence during the pandemic.Methods Eight patients who were diagnosed as having TB in Meram Medical Faculty, Necmettin Erbakan University between March 1, 2020, and December 31, 2021, at the beginning of the pandemic, were enrolled in this study. The presence of COVID-19 infection was confirmed using COVID-19 antibody tests and the patients' COVID-19 history. We evaluated the demographic data, laboratory findings, imaging tests, and pathology results of all patients. Results We checked all our patients with TB using COVID-19 antibodies (immunoglobulin [Ig]G thorn IgM) or polymerase chain reaction. Seven of the eight patients were female (87.5%). The median age was 16 years. Family screening of all patients was negative, and they had bacillus Calmette-Guerin vaccine scars. Two patients had chronic diseases. One was diagnosed as having primary ciliary dyskinesia in our department (patient no. 8) and the second was under follow-up by the rheumatology department with a diagnosis of juvenile idiopathic rheumatoid arthritis.Conclusion There has been an increase in the incidence of TB in children, especially in adolescents, during the pandemic period. This may be due to the pathogenic structure of the COVID-19 virus with an unknown mechanism. In addition, lifestyle changes and changes in health care policies during the pandemic may have caused this. Further research should be performed on this topic.en_US
dc.identifier.doi10.1055/s-0042-1760409
dc.identifier.endpage100en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85148659262en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage94en_US
dc.identifier.urihttps://doi.org/10.1055/s-0042-1760409
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12900
dc.identifier.volume18en_US
dc.identifier.wosWOS:000936029200006en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal Of Pediatric Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCovid-19en_US
dc.subjectTuberculosisen_US
dc.subjectReactivationen_US
dc.titleReactivation of Tuberculosis and COVID-19 in Pediatric Patientsen_US
dc.typeArticleen_US

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