Short-Term Safety of Paroxetine and Sertraline in Breastfed Infants: A Retrospective Cohort Study from a University Hospital

Basit Öğe Kaydı
dc.contributor.authorUguz, Faruk
dc.contributor.authorArpaci, Nazile
dc.date.accessioned2024-02-23T14:20:56Z
dc.date.available2024-02-23T14:20:56Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractObjective: Primary pharmacological agents for depression and anxiety disorders are antidepressants, especially selective serotonine reuptake inhibitors. The aim of this study was to examine the features and prevalence of adverse effects of paroxetine and sertraline in breastfed infants. Methods: The study had a retrospective cohort design. Five-year clinical data of 72 patients were included in the study. Psychiatric diagnoses were ascertained by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Results: The prevalence rate of adverse events in the infants was 12.5%. Insomnia (88.9%), restlessness (55.6%), and constant crying (22.2%) were the most frequent adverse events. A switch between paroxetine and sertraline performed in five patients, who reported an adverse event in their breastfed infants, resulted in cessation of the adverse events. Conclusion: The results suggest that the prevalence rate of adverse events in the infants exposed to sertraline or paroxetine is relatively low and mostly mild.en_US
dc.identifier.doi10.1089/bfm.2016.0095
dc.identifier.endpage489en_US
dc.identifier.issn1556-8253
dc.identifier.issn1556-8342
dc.identifier.issue9en_US
dc.identifier.pmid27575664en_US
dc.identifier.scopus2-s2.0-84995487695en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage487en_US
dc.identifier.urihttps://doi.org/10.1089/bfm.2016.0095
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13348
dc.identifier.volume11en_US
dc.identifier.wosWOS:000387209700013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofBreastfeeding Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreastfeedingen_US
dc.subjectSertralineen_US
dc.subjectParoxetineen_US
dc.subjectLactationen_US
dc.subjectInfanten_US
dc.titleShort-Term Safety of Paroxetine and Sertraline in Breastfed Infants: A Retrospective Cohort Study from a University Hospitalen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu