Application of L-prolinamides as highly efficient organocatalysts for the asymmetric Michael addition of unmodified aldehydes to nitroalkenes

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dc.contributor.authorNaziroglu, Hayriye Nevin
dc.contributor.authorDurmaz, Mustafa
dc.contributor.authorBozkurt, Selahattin
dc.contributor.authorDemir, Ayhan Sitki
dc.contributor.authorSirit, Abdulkadir
dc.date.accessioned2024-02-23T14:16:21Z
dc.date.available2024-02-23T14:16:21Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractThe asymmetric Michael addition of aldehydes to nitroolefins was investigated using a combination of L-prolinamide derivatives and various acidic additives. (S)-1,1'-Bi-2-naphthol was found to be the most effective co-catalyst and afforded the nitroaldehyde products with excellent yields (up to 95%), enantiomeric excesses (up to 99%) and diastereoselectivity ratios (up to 99:1). (C) 2012 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey [TUBITAK-109T167]en_US
dc.description.sponsorshipWe are grateful for the grants from the Scientific and Technical Research Council of Turkey (TUBITAK-109T167).en_US
dc.identifier.doi10.1016/j.tetasy.2012.01.008
dc.identifier.endpage169en_US
dc.identifier.issn0957-4166
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84858280792en_US
dc.identifier.startpage164en_US
dc.identifier.urihttps://doi.org/10.1016/j.tetasy.2012.01.008
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12635
dc.identifier.volume23en_US
dc.identifier.wosWOS:000302663700010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTetrahedron-Asymmetryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleApplication of L-prolinamides as highly efficient organocatalysts for the asymmetric Michael addition of unmodified aldehydes to nitroalkenesen_US
dc.typeArticleen_US

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