A flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensing

Basit Öğe Kaydı
dc.contributor.authorBulut, Umut
dc.contributor.authorSayin, Vuslat Oyku
dc.contributor.authorAltin, Yasin
dc.contributor.authorCevher, Sevki Can
dc.contributor.authorCirpan, Ali
dc.contributor.authorBedeloglu, Ayse Celik
dc.contributor.authorSoylemez, Saniye
dc.date.accessioned2024-02-23T14:13:16Z
dc.date.available2024-02-23T14:13:16Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractHerein, a specific and stable biosensor for glucose using a flexible, modified electrode with a carbon nanofiber (CNF) and a novel conjugated polymer including three moieties of benzotriazole, benzodithiophene, and benzenediamine (P-BDT-BTz:BDA) as a platform was designed. For this purpose, polyacrylonitrile (PAN) nanofiber mats were obtained by a solution-based electrospinning method. PAN nanofiber mats were stabilized and carbonized to turn into carbon nanofibers and the sensing platform was formed by combining the nanofibers on a defined area of a flexible polyethylene terephthalate (PET) substrate. In addition, a random conjugated polymer, P-BDT-BTz:BDA, was synthesized, characterized, and used as a modifier of a CNF-coated transducer surface for glucose detection. The effect of each parameter on biosensor response was evaluated. Under optimized conditions, the electrode responded to glucose in a linear concentration range of 20 mu M to 500 mu M with a detection limit of 8.5 mu M. In addition, it was observed that the designed biosensor has a good sensing ability for glucose in beverages. The results of our study show that the proposed amperometric glucose oxidase (GOx)-based biosensor has high specificity, a low limit of detection, and an extended range of linear detection for glucose.en_US
dc.identifier.doi10.1016/j.microc.2022.108148
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85142124632en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.microc.2022.108148
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12354
dc.identifier.volume184en_US
dc.identifier.wosWOS:001004016700001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMicrochemical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlucose Detectionen_US
dc.subjectCarbon Nanofiberen_US
dc.subjectConjugated Random Polymeren_US
dc.subjectEnzyme Immobilizationen_US
dc.subjectGlucose Oxidaseen_US
dc.titleA flexible carbon nanofiber and conjugated polymer-based electrode for glucose sensingen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu