Evaluation of Postmortem Cerebrospinal Fluid S100B Protein and Serotonin Levels: Comparison of Suicidal Versus Nonsuicidal Deaths in Konya, Turkey

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dc.contributor.authorDogan, Kamil Hakan
dc.contributor.authorUnaldi, Mustafa
dc.contributor.authorDemirci, Serafettin
dc.date.accessioned2024-02-23T14:23:59Z
dc.date.available2024-02-23T14:23:59Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractAlthough suicide is a preventable public health problem, objective assays for suicide risk are limited. In this study, it was aimed to determine levels of S100B protein and serotonin as a marker for risk of suicide. S100B protein and serotonin levels were investigated with ELISA method in the cerebrospinal fluid (CSF) in medicolegal autopsy cases, including those of suicide cases (n = 32) and nonsuicide cases (n = 56). The CSF S100B levels were higher (9.3 +/- 2.9 ng/mL vs. 5.4 +/- 2.0 ng/mL), and serotonin levels were lower (10.4 +/- 4.9 ng/mL vs. 19.0 +/- 5.7 ng/mL) in suicide group than nonsuicide group (p < 0.05). There was no correlation between S100B protein and serotonin levels with gender, age groups, postmortem interval, and cause of death. It is concluded that both S100B protein and serotonin in CSF may be useful for determination of suicide risk.en_US
dc.description.sponsorshipScientific Research Projects Coordinating Office of Selcuk University [11102026]en_US
dc.description.sponsorshipFunded by Scientific Research Projects Coordinating Office of Selcuk University (Project Number: 11102026).en_US
dc.identifier.doi10.1111/1556-4029.13124
dc.identifier.endpage1291en_US
dc.identifier.issn0022-1198
dc.identifier.issn1556-4029
dc.identifier.issue5en_US
dc.identifier.pmid27282656en_US
dc.identifier.scopus2-s2.0-85027917203en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1285en_US
dc.identifier.urihttps://doi.org/10.1111/1556-4029.13124
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13753
dc.identifier.volume61en_US
dc.identifier.wosWOS:000383366800017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofJournal Of Forensic Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectForensic Scienceen_US
dc.subjectS100ben_US
dc.subjectSerotoninen_US
dc.subjectPostmortemen_US
dc.subjectSuicideen_US
dc.subjectDeathen_US
dc.titleEvaluation of Postmortem Cerebrospinal Fluid S100B Protein and Serotonin Levels: Comparison of Suicidal Versus Nonsuicidal Deaths in Konya, Turkeyen_US
dc.typeArticleen_US

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