Evaluation of malnutrition risk and nutrition status in adult patients with common variable immunodeficiency

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dc.contributor.authorYildiz, Eray
dc.contributor.authorArslan, Sevket
dc.contributor.authorColkesen, Fatih
dc.contributor.authorAykan, Filiz Sadi
dc.contributor.authorEvcen, Recep
dc.contributor.authorKilinc, Mehmet
dc.contributor.authorAytekin, Gokhan
dc.date.accessioned2024-02-23T13:03:28Z
dc.date.available2024-02-23T13:03:28Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground The aim of this study is to determine the prevalence of malnutrition in outpatients with common variable immunodeficiency (CVID) and the utility of nutrition screening tools to detect malnutrition in these patients. Methods Fifty outpatients with CVID were included in the study. Nutrition risk for each patient was evaluated using four nutrition screening tools: Malnutrition Screening Tool (MST), Malnutrition Universal Screening Tool (MUST), Short Nutritional Assessment Questionnaire (SNAQ), and Nutritional Risk Screening 2002 (NRS-2002). Results According to MUST, MST, SNAQ, and NRS-2002, malnutrition risk was determined to be 48% (n = 24), 26% (n = 13), 20% (n = 10), and 20% (n = 10), respectively. Malnutrition was detected in 54% (n = 27) of the patients. It was found that MUST showed a better correlation in detecting malnutrition in outpatients with CVID (kappa = 0.482, P = 0.001). MUST has a higher positive and negative predictive value than other nutrition screening tools (79% and 70%, respectively). In the multivariate logistic regression analysis, it was found that low serum immunoglobulin A (IgA) levels at diagnosis increased the risk of malnutrition by similar to 15 times, and low CD19(+) B-cell counts increased the risk by approximately eight times. Conclusion The prevalence of malnutrition in patients with CVID was found to be quite high, and there was a strong correlation between malnutrition and low CD19(+) B-cell counts and low serum IgA levels. Given the high rate of malnutrition in patients with CVID, nutrition assessment is recommended rather than starting with nutrition screening.en_US
dc.identifier.doi10.1002/ncp.10806
dc.identifier.endpage1214en_US
dc.identifier.issn0884-5336
dc.identifier.issn1941-2452
dc.identifier.issue5en_US
dc.identifier.pmid34989028en_US
dc.identifier.scopus2-s2.0-85122284201en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1206en_US
dc.identifier.urihttps://doi.org/10.1002/ncp.10806
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10629
dc.identifier.volume37en_US
dc.identifier.wosWOS:000739140500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNutrition In Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCommon Variable Immunodeficiencyen_US
dc.subjectMalnutritionen_US
dc.subjectNutrition Assessmenten_US
dc.subjectNutrition Screeningen_US
dc.titleEvaluation of malnutrition risk and nutrition status in adult patients with common variable immunodeficiencyen_US
dc.typeArticleen_US

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