Oxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disorders

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dc.contributor.authorUzun, Necati
dc.contributor.authorAkca, Omer Faruk
dc.contributor.authorKilinc, Ibrahim
dc.contributor.authorBalci, Tevfik
dc.date.accessioned2024-02-23T14:44:57Z
dc.date.available2024-02-23T14:44:57Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractObjective: This study aimed to determine whether a difference exists in plasma oxytocin and vasopressin levels among social anxiety disorder, other anxiety disorders, and healthy control groups in adolescents. The relationship between several psychiatric variables (i.e., state and trait anxiety, social anxiety, childhood trauma, and behavioral inhibition) and oxytocin or vasopressin levels were also investigated in adolescents with anxiety disorders. Methods: The study included three groups of adolescents: social anxiety disorder (n = 29), those with other anxiety disorders (n = 27), and the control group (n = 28). The participants filled out self-report scales to determine various psychological variables. Oxytocin and vasopressin levels were determined from the blood samples of the participants. Results: The oxytocin levels did not show a significant difference between the social anxiety disorder group and the other anxiety disorders group. However, the oxytocin levels were significantly higher in the social anxiety disorder and other anxiety disorders groups than in the control group. The vasopressin levels did not show a significant difference among the groups. According to the hierarchical regression analysis, the state and trait anxiety levels predicted oxytocin in opposite directions. Oxytocin showed positive and negative relationship with trait and state anxiety respectively. No predictive factors were found for the vasopressin levels. Conclusion: We found that the oxytocin levels of adolescents with social anxiety disorder were not different from those of adolescents with other anxiety disorders. Further studies can improve our knowledge of the relationship among anxiety disorders and oxytocin or vasopressin.en_US
dc.description.sponsorshipScientific Research Project Coordination Unit of Necmettin Erbakan University [161518023]en_US
dc.description.sponsorshipFunding for this study was provided by a grant from the Scientific Research Project Coordination Unit of Necmettin Erbakan University (Project no. 161518023).en_US
dc.identifier.doi10.9758/cpn.2022.20.2.330
dc.identifier.endpage342en_US
dc.identifier.issn1738-1088
dc.identifier.issn2093-4327
dc.identifier.issue2en_US
dc.identifier.pmid35466104en_US
dc.identifier.scopus2-s2.0-85132593957en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage330en_US
dc.identifier.urihttps://doi.org/10.9758/cpn.2022.20.2.330
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17170
dc.identifier.volume20en_US
dc.identifier.wosWOS:000792520700003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Coll Neuropsychopharmacologyen_US
dc.relation.ispartofClinical Psychopharmacology And Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnxiety Disordersen_US
dc.subjectBehavioral Inhibitionen_US
dc.subjectOxytocinen_US
dc.subjectSocial Phobiaen_US
dc.subjectVasopressinen_US
dc.titleOxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disordersen_US
dc.typeArticleen_US

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