Association between depression and anxiety scores and inflammation in patients wain isolated coronary artery ectasia

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dc.contributor.authorGurbuz, Ahmet Seyfeddin
dc.contributor.authorAlsancak, Yakup
dc.contributor.authorSakli, Beyza
dc.contributor.authorDuzenli, Mehmet Akif
dc.date.accessioned2024-02-23T14:41:43Z
dc.date.available2024-02-23T14:41:43Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractObjective: Depression and anxiety disorders are frequently found in combination with obstructive coronary artery disease. Coronary artery ectasia (CAE) is an atypical form of coronary artery disease, the etiology of which has not yet been clearly defined. The aim of this study was to assess the existence of a relationship between anxiety/depression and CAE. Methods: A CAE group (n=41; mean age: 58.9 +/- 9.0 years) and a control group (n=42; mean age: 58.0 +/- 9.6 years) were compared. The anxiety and depression status of patients was evaluated using the Hospital Anxiety and Depression Scale (HADS) questionnaire. Results: Age, sex, ejection fraction, and cardiovascular risk factor data were similar in both groups. The serum C-reactive protein (CRP) and uric acid levels as well as the leukocyte count were significantly higher in the CAE group (p<0.05). The HADS anxiety score was higher in the CAE group, but without statistical significance (p=0.23). The HADS depression score and total HADS score was significantly higher in the CAE group (p<0.001 and p<0.001). The total HADS score and the HADS depression score were correlated with the serum CRP level (r=0.489; p<0.001 and r=0.543; p<0.001, respectively), whereas the anxiety score was not correlated with CRP (r=0.85; p=0.23). Conclusion: The depression score, CRP, and uric acid levels were greater in patients with isolated CAE compared with those of patients with normal coronaries. The anxiety score did not demonstrate a relationship to CAE; however, there was an association between the depression score and CRP, which is an inflammatory marker.en_US
dc.identifier.doi10.5543/tkda.2019.45403
dc.identifier.endpage372en_US
dc.identifier.issn1016-5169
dc.identifier.issue5en_US
dc.identifier.pmid31311901en_US
dc.identifier.scopus2-s2.0-85068792782en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage365en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2019.45403
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16962
dc.identifier.volume47en_US
dc.identifier.wosWOS:000475438700004en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives Of The Turkish Society Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnxietyen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectCoronary Artery Ectasiaen_US
dc.subjectDepressionen_US
dc.titleAssociation between depression and anxiety scores and inflammation in patients wain isolated coronary artery ectasiaen_US
dc.typeArticleen_US

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