Serum ischemia-modified albumin and oxidized LDL in cord blood and serum of neonates born to pre-eclamptic mothers

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dc.contributor.authorMehmetoglu, Idris
dc.contributor.authorKurban, Sevil
dc.contributor.authorToker, Aysun
dc.contributor.authorAnnaguer, Ali
dc.contributor.authorAltunhan, Huseyin
dc.contributor.authorErbay, Ekrem
dc.contributor.authorOrs, Rahmi
dc.date.accessioned2024-02-23T14:24:35Z
dc.date.available2024-02-23T14:24:35Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBackgroundWe investigated oxidized low-density lipoprotein (OxLDL) and ischemia-modified albumin (IMA) in cord blood and neonatal blood of 7-day-old neonates born to pre-eclamptic and normotensive healthy mothers. MethodsThe study was performed on 30 neonates born to pre-eclamptic and 20 neonates born to normotensive mothers. IMA and OxLDL were determined on spectrophotometry and ELISA, respectively. ResultsIMA in cord blood was higher in the pre-eclamptic group as compared with the normotensive group, but the difference between the groups was not significant. IMA in neonate venous blood was significantly higher in the pre-eclamptic group than in the normotensive group (P < 0.001). OxLDL in both cord blood and in neonate venous blood was significantly higher in the pre-eclamptic group compared with the normotensive group (P < 0.001). IMA and OxLDL were significantly decreased after delivery in both groups. ConclusionsSignificantly increased cord blood OxLDL and significantly increased OxLDL and IMA 7days after birth in neonates born to pre-eclamptic mothers might be an indicator of increased oxidative stress in pre-eclampsia.en_US
dc.identifier.doi10.1111/ped.12552
dc.identifier.endpage426en_US
dc.identifier.issn1328-8067
dc.identifier.issn1442-200X
dc.identifier.issue3en_US
dc.identifier.pmid25444362en_US
dc.identifier.scopus2-s2.0-84933531599en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage422en_US
dc.identifier.urihttps://doi.org/10.1111/ped.12552
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14022
dc.identifier.volume57en_US
dc.identifier.wosWOS:000356974900015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCord Blooden_US
dc.subjectIschemia-Modified Albuminen_US
dc.subjectNeonate Born To Pre-Eclamptic Motheren_US
dc.subjectOxidized Low-Density Lipoproteinen_US
dc.subjectPre-Eclampsiaen_US
dc.titleSerum ischemia-modified albumin and oxidized LDL in cord blood and serum of neonates born to pre-eclamptic mothersen_US
dc.typeArticleen_US

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